pubmed-article:12515583 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:12515583 | lifeskim:mentions | umls-concept:C0033684 | lld:lifeskim |
pubmed-article:12515583 | lifeskim:mentions | umls-concept:C0237753 | lld:lifeskim |
pubmed-article:12515583 | lifeskim:mentions | umls-concept:C0439857 | lld:lifeskim |
pubmed-article:12515583 | lifeskim:mentions | umls-concept:C0015219 | lld:lifeskim |
pubmed-article:12515583 | lifeskim:mentions | umls-concept:C0872079 | lld:lifeskim |
pubmed-article:12515583 | lifeskim:mentions | umls-concept:C1521828 | lld:lifeskim |
pubmed-article:12515583 | lifeskim:mentions | umls-concept:C0439834 | lld:lifeskim |
pubmed-article:12515583 | lifeskim:mentions | umls-concept:C0205352 | lld:lifeskim |
pubmed-article:12515583 | pubmed:dateCreated | 2003-10-29 | lld:pubmed |
pubmed-article:12515583 | pubmed:abstractText | It has been suggested that rates of protein evolution are influenced, to a great extent, by the proportion of amino acid residues that are directly involved in protein function. In agreement with this hypothesis, recent work has shown a negative correlation between evolutionary rates and the number of protein-protein interactions. However, the extent to which the number of protein-protein interactions influences evolutionary rates remains unclear. Here, we address this question at several different levels of evolutionary relatedness. | lld:pubmed |
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pubmed-article:12515583 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
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pubmed-article:12515583 | pubmed:language | eng | lld:pubmed |
pubmed-article:12515583 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:12515583 | pubmed:citationSubset | IM | lld:pubmed |
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pubmed-article:12515583 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
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pubmed-article:12515583 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:12515583 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:12515583 | pubmed:month | Jan | lld:pubmed |
pubmed-article:12515583 | pubmed:issn | 1471-2148 | lld:pubmed |
pubmed-article:12515583 | pubmed:author | pubmed-author:KooninEugene... | lld:pubmed |
pubmed-article:12515583 | pubmed:author | pubmed-author:WolfYuri IYI | lld:pubmed |
pubmed-article:12515583 | pubmed:author | pubmed-author:JordanI... | lld:pubmed |
pubmed-article:12515583 | pubmed:issnType | Electronic | lld:pubmed |
pubmed-article:12515583 | pubmed:day | 6 | lld:pubmed |
pubmed-article:12515583 | pubmed:volume | 3 | lld:pubmed |
pubmed-article:12515583 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:12515583 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:12515583 | pubmed:pagination | 1 | lld:pubmed |
pubmed-article:12515583 | pubmed:dateRevised | 2010-9-14 | lld:pubmed |
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pubmed-article:12515583 | pubmed:year | 2003 | lld:pubmed |
pubmed-article:12515583 | pubmed:articleTitle | No simple dependence between protein evolution rate and the number of protein-protein interactions: only the most prolific interactors tend to evolve slowly. | lld:pubmed |
pubmed-article:12515583 | pubmed:affiliation | National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, MD 20894, USA. jordan@ncbi.nlm.nih.gov | lld:pubmed |
pubmed-article:12515583 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:12515583 | pubmed:publicationType | Comparative Study | lld:pubmed |
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