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pubmed-article:12437097pubmed:abstractTextActivated T lymphocytes express high levels of dipeptidyl peptidase IV (DP IV)/CD26. Recent studies support the notion that DP IV may play an important role in the regulation of differentiation and growth of T lymphocytes. This article gives a short overview on DP IV/CD26 expression and effects on immune cells in vitro and in vivo. A major focus of this review are clinical aspects of the function of CD26 on hematopoietic cells and the potential usage of synthetic DP IV inhibitors as therapeutics in inflammatory disorders.lld:pubmed
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pubmed-article:12437097pubmed:authorpubmed-author:NeubertKlausKlld:pubmed
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pubmed-article:12437097pubmed:pagination1133-8lld:pubmed
pubmed-article:12437097pubmed:dateRevised2010-11-18lld:pubmed
pubmed-article:12437097pubmed:articleTitleThe role of dipeptidyl peptidase IV (DP IV) enzymatic activity in T cell activation and autoimmunity.lld:pubmed
pubmed-article:12437097pubmed:affiliationInstitute of Immunology, Otto-von-Gueircke University Magdeburg, Germany.lld:pubmed
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