| pubmed-article:12388322 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:12388322 | lifeskim:mentions | umls-concept:C0003842 | lld:lifeskim |
| pubmed-article:12388322 | lifeskim:mentions | umls-concept:C0442025 | lld:lifeskim |
| pubmed-article:12388322 | lifeskim:mentions | umls-concept:C0205127 | lld:lifeskim |
| pubmed-article:12388322 | lifeskim:mentions | umls-concept:C0441247 | lld:lifeskim |
| pubmed-article:12388322 | lifeskim:mentions | umls-concept:C1280500 | lld:lifeskim |
| pubmed-article:12388322 | pubmed:issue | 6 | lld:pubmed |
| pubmed-article:12388322 | pubmed:dateCreated | 2002-11-12 | lld:pubmed |
| pubmed-article:12388322 | pubmed:abstractText | With progressing age, large arteries diminish their longitudinal stretch, which in extreme cases results in tortuosity. Increased age is also associated with loss of vessel distensibility. We measured pressure-diameter curves from muscular porcine carotid arteries ex vivo at different longitudinal stretch ratios (lambda(z) = 1.4 and 1.8) and under different vascular smooth muscle (VSM) conditions (fully relaxed, normal VSM tone, and maximally contracted). Distensibility was found to be halved by decreasing longitudinal stretch from lambda(z) = 1.8 to 1.4 at physiological pressures. This counterintuitive observation is possible because highly nonlinear elastic modulus of the artery and anisotropic properties. Furthermore, a significantly larger basal VSM contraction was observed at lambda(z) = 1.8 than 1.4, although this was clearly not related to a myogenic response during inflation. This dependence of VSM tone to longitudinal stretch may have possible implications on the functional characteristics of the arterial wall. | lld:pubmed |
| pubmed-article:12388322 | pubmed:language | eng | lld:pubmed |
| pubmed-article:12388322 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12388322 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:12388322 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:12388322 | pubmed:month | Dec | lld:pubmed |
| pubmed-article:12388322 | pubmed:issn | 0363-6135 | lld:pubmed |
| pubmed-article:12388322 | pubmed:author | pubmed-author:StergiopulosN... | lld:pubmed |
| pubmed-article:12388322 | pubmed:author | pubmed-author:ZulligerMarti... | lld:pubmed |
| pubmed-article:12388322 | pubmed:author | pubmed-author:KwakNaomi T... | lld:pubmed |
| pubmed-article:12388322 | pubmed:author | pubmed-author:TsapikouniThe... | lld:pubmed |
| pubmed-article:12388322 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:12388322 | pubmed:volume | 283 | lld:pubmed |
| pubmed-article:12388322 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:12388322 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:12388322 | pubmed:pagination | H2599-605 | lld:pubmed |
| pubmed-article:12388322 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:12388322 | pubmed:meshHeading | pubmed-meshheading:12388322... | lld:pubmed |
| pubmed-article:12388322 | pubmed:meshHeading | pubmed-meshheading:12388322... | lld:pubmed |
| pubmed-article:12388322 | pubmed:meshHeading | pubmed-meshheading:12388322... | lld:pubmed |
| pubmed-article:12388322 | pubmed:meshHeading | pubmed-meshheading:12388322... | lld:pubmed |
| pubmed-article:12388322 | pubmed:meshHeading | pubmed-meshheading:12388322... | lld:pubmed |
| pubmed-article:12388322 | pubmed:meshHeading | pubmed-meshheading:12388322... | lld:pubmed |
| pubmed-article:12388322 | pubmed:meshHeading | pubmed-meshheading:12388322... | lld:pubmed |
| pubmed-article:12388322 | pubmed:meshHeading | pubmed-meshheading:12388322... | lld:pubmed |
| pubmed-article:12388322 | pubmed:meshHeading | pubmed-meshheading:12388322... | lld:pubmed |
| pubmed-article:12388322 | pubmed:meshHeading | pubmed-meshheading:12388322... | lld:pubmed |
| pubmed-article:12388322 | pubmed:meshHeading | pubmed-meshheading:12388322... | lld:pubmed |
| pubmed-article:12388322 | pubmed:meshHeading | pubmed-meshheading:12388322... | lld:pubmed |
| pubmed-article:12388322 | pubmed:year | 2002 | lld:pubmed |
| pubmed-article:12388322 | pubmed:articleTitle | Effects of longitudinal stretch on VSM tone and distensibility of muscular conduit arteries. | lld:pubmed |
| pubmed-article:12388322 | pubmed:affiliation | Laboratory of Hemodynamics and Cardiovascular Technologies, Swiss Federal Institute of Technology, 1015 Lausanne, Switzerland. martin.zulliger@epfl.ch | lld:pubmed |
| pubmed-article:12388322 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:12388322 | pubmed:publicationType | In Vitro | lld:pubmed |
| pubmed-article:12388322 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:12388322 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:12388322 | lld:pubmed |
