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pubmed-article:12385442pubmed:abstractTextTumor necrosis factor-alpha (TNF-alpha) is an important cytokine involved in the pathogenesis of inflammatory bowel disease. The monoclonal antibody to TNF-alpha, infliximab, is effective in treating Crohn's disease. Preclinical studies suggest the importance of TNF-alpha in treating ulcerative colitis (UC). We report the effectiveness of infliximab for UC and examine factors predictive of response to medication.lld:pubmed
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pubmed-article:12385442pubmed:articleTitleEfficacy of anti-tumor necrosis factor therapy in patients with ulcerative colitis.lld:pubmed
pubmed-article:12385442pubmed:affiliationDepartment of Medicine, University of Pennsylvania School of Medicine, Philadelphia 19104-4283, USA.lld:pubmed
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