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pubmed-article:12359959pubmed:abstractTextChemokines are key regulators of leukocyte traffic in various forms of inflammation and reperfusion injury. There is emerging evidence that the activation of the nuclear enzyme poly(ADP-ribose) polymerase (PARP) importantly contributes to the up-regulation of a variety of proinflammatory signal transduction pathways and associated genes.lld:pubmed
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pubmed-article:12359959pubmed:articleTitlePoly(ADP-ribose) polymerase is a regulator of chemokine production: relevance for the pathogenesis of shock and inflammation.lld:pubmed
pubmed-article:12359959pubmed:affiliationInotek Pharmaceuticals Corporation, Beverly, Massachusetts 01915, USA.lld:pubmed
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