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pubmed-article:12242135pubmed:abstractTextObjective: Streptococcus pneumoniae is the most common pathogen in otitis media. Infection of the middle ear with S. pneumoniae potentiates development of thick effusion in the middle ear which frequently causes hearing loss and communication disorders in children. What has changed immediately in the middle ear cleft following pneumococcal infection is extensively studied and characterized but what has changed ever after remains elusive. The purpose of this study is to explore the cellular and molecular basis that remains on a longer time after acute pneucmococcal middle ear infection and potentiates development of thick effusion in the middle ear.lld:pubmed
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pubmed-article:12242135pubmed:articleTitleAnalysis by cDNA microarrays of altered gene expression in middle ears of rats following pneumococcal infection.lld:pubmed
pubmed-article:12242135pubmed:affiliationDepartment of Otolaryngology, University of Minnesota Otitis Media Research Center, University of Minnesota School of Medicine, 2001 Sixth Street S.E., Room 216, Minneapolis, MN 55455, USA. linxx004@tc.umn.edulld:pubmed
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pubmed-article:12242135pubmed:publicationTypeResearch Support, U.S. Gov't, P.H.S.lld:pubmed
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