| pubmed-article:12122490 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:12122490 | lifeskim:mentions | umls-concept:C0025914 | lld:lifeskim |
| pubmed-article:12122490 | lifeskim:mentions | umls-concept:C0026809 | lld:lifeskim |
| pubmed-article:12122490 | lifeskim:mentions | umls-concept:C0020672 | lld:lifeskim |
| pubmed-article:12122490 | lifeskim:mentions | umls-concept:C0312418 | lld:lifeskim |
| pubmed-article:12122490 | lifeskim:mentions | umls-concept:C0678304 | lld:lifeskim |
| pubmed-article:12122490 | lifeskim:mentions | umls-concept:C1704410 | lld:lifeskim |
| pubmed-article:12122490 | lifeskim:mentions | umls-concept:C1707391 | lld:lifeskim |
| pubmed-article:12122490 | lifeskim:mentions | umls-concept:C0036667 | lld:lifeskim |
| pubmed-article:12122490 | lifeskim:mentions | umls-concept:C0205265 | lld:lifeskim |
| pubmed-article:12122490 | lifeskim:mentions | umls-concept:C1553412 | lld:lifeskim |
| pubmed-article:12122490 | lifeskim:mentions | umls-concept:C1548328 | lld:lifeskim |
| pubmed-article:12122490 | lifeskim:mentions | umls-concept:C1555582 | lld:lifeskim |
| pubmed-article:12122490 | pubmed:issue | 3 | lld:pubmed |
| pubmed-article:12122490 | pubmed:dateCreated | 2002-7-17 | lld:pubmed |
| pubmed-article:12122490 | pubmed:abstractText | Acute ethanol administration induces hypothermia in genetically susceptible animals. Tolerance to this effect may develop with repeated administration. Allopregnanolone is an endogenously produced neuroactive steroid that acts at the GABA-A receptor. We postulated that allopregnanolone would induce hypothermia, and that lines of mice selectively bred for high (COLD-1 and COLD-2) or low (HOT-1 and HOT-2) sensitivity to ethanol's hypothermic effects would also be differentially sensitive to allopregnanolone-induced hypothermia. We also postulated that tolerance would develop to these two drugs by similar mechanisms, such that tolerance to one would impart cross-tolerance to the other. | lld:pubmed |
| pubmed-article:12122490 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
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| pubmed-article:12122490 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12122490 | pubmed:language | eng | lld:pubmed |
| pubmed-article:12122490 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12122490 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:12122490 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
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| pubmed-article:12122490 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12122490 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:12122490 | pubmed:month | Jul | lld:pubmed |
| pubmed-article:12122490 | pubmed:issn | 0033-3158 | lld:pubmed |
| pubmed-article:12122490 | pubmed:author | pubmed-author:CrabbeJohn... | lld:pubmed |
| pubmed-article:12122490 | pubmed:author | pubmed-author:PalmerAbraham... | lld:pubmed |
| pubmed-article:12122490 | pubmed:author | pubmed-author:PhillipsTamar... | lld:pubmed |
| pubmed-article:12122490 | pubmed:author | pubmed-author:MoyerMichelle... | lld:pubmed |
| pubmed-article:12122490 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:12122490 | pubmed:volume | 162 | lld:pubmed |
| pubmed-article:12122490 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:12122490 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:12122490 | pubmed:pagination | 313-22 | lld:pubmed |
| pubmed-article:12122490 | pubmed:dateRevised | 2007-11-14 | lld:pubmed |
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| pubmed-article:12122490 | pubmed:meshHeading | pubmed-meshheading:12122490... | lld:pubmed |
| pubmed-article:12122490 | pubmed:year | 2002 | lld:pubmed |
| pubmed-article:12122490 | pubmed:articleTitle | Initial sensitivity, tolerance and cross-tolerance to allopregnanolone- and ethanol-induced hypothermia in selected mouse lines. | lld:pubmed |
| pubmed-article:12122490 | pubmed:affiliation | Portland Alcohol Research Center, Portland, OR 97201, USA. | lld:pubmed |
| pubmed-article:12122490 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:12122490 | pubmed:publicationType | Comparative Study | lld:pubmed |
| pubmed-article:12122490 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:12122490 | pubmed:publicationType | Research Support, U.S. Gov't, Non-P.H.S. | lld:pubmed |
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