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pubmed-article:12070051pubmed:abstractTextHydrops fetalis is rarely caused by congenital dyserythropoietic anemia (CDA). We report a patient with hydrops fetalis as a result of severe anemia. This patient needed intrauterine transfusions from 21 weeks of gestation until birth. The hematologic study showed an atypical CDA (hydrops fetalis-associated CDA) characterized by features resembling CDA type II, but negative acidified serum lysis test (HEMPAS negative). The patient was regularly transfused for a year, after which an allogeneic bone marrow transplantation (BMT) from an HLA-identical sibling was successfully carried out. His actual hemoglobin is 127 g/L, and he has not received transfusions for more than a year. In conclusion, intrauterine transfusions and BMT could cure an otherwise lethal atypical CDA.lld:pubmed
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pubmed-article:12070051pubmed:articleTitleHydrops fetalis-associated congenital dyserythropoietic anemia treated with intrauterine transfusions and bone marrow transplantation.lld:pubmed
pubmed-article:12070051pubmed:affiliationDepartment of Hematology, Hospital Santa Creu i Sant Pau, Barcelona, Spain.lld:pubmed
pubmed-article:12070051pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:12070051pubmed:publicationTypeCase Reportslld:pubmed
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