| pubmed-article:12039735 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:12039735 | lifeskim:mentions | umls-concept:C0036025 | lld:lifeskim |
| pubmed-article:12039735 | lifeskim:mentions | umls-concept:C0004038 | lld:lifeskim |
| pubmed-article:12039735 | lifeskim:mentions | umls-concept:C0017837 | lld:lifeskim |
| pubmed-article:12039735 | lifeskim:mentions | umls-concept:C0043335 | lld:lifeskim |
| pubmed-article:12039735 | lifeskim:mentions | umls-concept:C0347988 | lld:lifeskim |
| pubmed-article:12039735 | lifeskim:mentions | umls-concept:C0079429 | lld:lifeskim |
| pubmed-article:12039735 | lifeskim:mentions | umls-concept:C0683598 | lld:lifeskim |
| pubmed-article:12039735 | lifeskim:mentions | umls-concept:C1880177 | lld:lifeskim |
| pubmed-article:12039735 | lifeskim:mentions | umls-concept:C2700640 | lld:lifeskim |
| pubmed-article:12039735 | lifeskim:mentions | umls-concept:C2348205 | lld:lifeskim |
| pubmed-article:12039735 | pubmed:issue | 6 | lld:pubmed |
| pubmed-article:12039735 | pubmed:dateCreated | 2002-5-31 | lld:pubmed |
| pubmed-article:12039735 | pubmed:abstractText | Aspergillus nidulans is a saprophytic ascomycete that utilizes a wide variety of nitrogen sources. We identified a sequence from A. nidulans similar to the glutathione S-transferase-like nitrogen regulatory domain of Saccharomyces cerevisiae Ure2. Cloning and sequencing of the gene, designated gstA, revealed it to be more similar to URE2 than the S. cerevisiae glutathione S-transferases. However, creation and analysis of a gstA deletion mutant revealed that the gene does not participate in nitrogen metabolite repression. Instead, it encodes a functional theta class glutathione S-transferase that is involved in resistance to a variety of xenobiotics and metals and confers susceptibility to the systemic fungicide carboxin. Northern analysis showed that gstA transcription is strongly activated upon exposure to 1-chloro-2,4-dinitrobenzene and weakly activated by oxidative stress or growth on galactose as a carbon source. These results suggest that nitrogen metabolite repression in A. nidulans does not involve a homolog of the S. cerevisiae URE2 gene and that the global nitrogen regulatory system differs significantly in these two fungi. | lld:pubmed |
| pubmed-article:12039735 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12039735 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12039735 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12039735 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12039735 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12039735 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12039735 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12039735 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12039735 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12039735 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12039735 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12039735 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12039735 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12039735 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12039735 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12039735 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12039735 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12039735 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12039735 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12039735 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12039735 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12039735 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12039735 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12039735 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12039735 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12039735 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12039735 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12039735 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12039735 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12039735 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12039735 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12039735 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12039735 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12039735 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12039735 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12039735 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12039735 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12039735 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12039735 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12039735 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12039735 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12039735 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12039735 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12039735 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12039735 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12039735 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12039735 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12039735 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12039735 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12039735 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12039735 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12039735 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12039735 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12039735 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12039735 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12039735 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12039735 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12039735 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12039735 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12039735 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12039735 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12039735 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12039735 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12039735 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12039735 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12039735 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12039735 | pubmed:language | eng | lld:pubmed |
| pubmed-article:12039735 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12039735 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:12039735 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12039735 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12039735 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12039735 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12039735 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12039735 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12039735 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12039735 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12039735 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12039735 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12039735 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12039735 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12039735 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:12039735 | pubmed:month | Jun | lld:pubmed |
| pubmed-article:12039735 | pubmed:issn | 0099-2240 | lld:pubmed |
| pubmed-article:12039735 | pubmed:author | pubmed-author:HynesMichael... | lld:pubmed |
| pubmed-article:12039735 | pubmed:author | pubmed-author:DavisMeryl... | lld:pubmed |
