| pubmed-article:12034051 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:12034051 | lifeskim:mentions | umls-concept:C0086418 | lld:lifeskim |
| pubmed-article:12034051 | lifeskim:mentions | umls-concept:C0332437 | lld:lifeskim |
| pubmed-article:12034051 | lifeskim:mentions | umls-concept:C0010453 | lld:lifeskim |
| pubmed-article:12034051 | lifeskim:mentions | umls-concept:C0009325 | lld:lifeskim |
| pubmed-article:12034051 | lifeskim:mentions | umls-concept:C0040136 | lld:lifeskim |
| pubmed-article:12034051 | lifeskim:mentions | umls-concept:C0431085 | lld:lifeskim |
| pubmed-article:12034051 | lifeskim:mentions | umls-concept:C0439158 | lld:lifeskim |
| pubmed-article:12034051 | lifeskim:mentions | umls-concept:C0205281 | lld:lifeskim |
| pubmed-article:12034051 | lifeskim:mentions | umls-concept:C0085732 | lld:lifeskim |
| pubmed-article:12034051 | lifeskim:mentions | umls-concept:C0017243 | lld:lifeskim |
| pubmed-article:12034051 | lifeskim:mentions | umls-concept:C1707520 | lld:lifeskim |
| pubmed-article:12034051 | lifeskim:mentions | umls-concept:C0205431 | lld:lifeskim |
| pubmed-article:12034051 | pubmed:issue | 4 | lld:pubmed |
| pubmed-article:12034051 | pubmed:dateCreated | 2002-5-29 | lld:pubmed |
| pubmed-article:12034051 | pubmed:abstractText | Two different types of colonies from human thyroid papillary carcinomas were observed in collagen gel culture. One was a branching type, with many three-dimensional outgrowths. The other was a spherical type, with no outgrowths. As viewed by electron microscopy, the tumor cells of spherical-type colonies had more microvilli on their surfaces than did cells in the branching-type colonies. Histochemically, the tumor cells of spherical-type colonies had stronger positive reactions than did tumor cells of branching-type colonies. This suggests that tumor cells of spherical-type colonies have a higher potential for dissemination and invasion than do tumor cells of branching-type colonies. In fact, cases with higher percentages of spherical-type colonies could show extracapsular invasion histopathologically. Our results indicate that collagen gel culture is a useful method for studying the heterogeneity of tumor cells as well as their invasive ability in vitro. | lld:pubmed |
| pubmed-article:12034051 | pubmed:language | eng | lld:pubmed |
| pubmed-article:12034051 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12034051 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:12034051 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12034051 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12034051 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12034051 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12034051 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12034051 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12034051 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:12034051 | pubmed:month | Apr | lld:pubmed |
| pubmed-article:12034051 | pubmed:issn | 1050-7256 | lld:pubmed |
| pubmed-article:12034051 | pubmed:author | pubmed-author:NishidaShozoS | lld:pubmed |
| pubmed-article:12034051 | pubmed:author | pubmed-author:KusunokiTakes... | lld:pubmed |
| pubmed-article:12034051 | pubmed:author | pubmed-author:MurataKiyotak... | lld:pubmed |
| pubmed-article:12034051 | pubmed:author | pubmed-author:TomuraTakanor... | lld:pubmed |
| pubmed-article:12034051 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:12034051 | pubmed:volume | 12 | lld:pubmed |
| pubmed-article:12034051 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:12034051 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:12034051 | pubmed:pagination | 281-6 | lld:pubmed |
| pubmed-article:12034051 | pubmed:dateRevised | 2007-11-15 | lld:pubmed |
| pubmed-article:12034051 | pubmed:meshHeading | pubmed-meshheading:12034051... | lld:pubmed |
| pubmed-article:12034051 | pubmed:meshHeading | pubmed-meshheading:12034051... | lld:pubmed |
| pubmed-article:12034051 | pubmed:meshHeading | pubmed-meshheading:12034051... | lld:pubmed |
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| pubmed-article:12034051 | pubmed:meshHeading | pubmed-meshheading:12034051... | lld:pubmed |
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| pubmed-article:12034051 | pubmed:meshHeading | pubmed-meshheading:12034051... | lld:pubmed |
| pubmed-article:12034051 | pubmed:meshHeading | pubmed-meshheading:12034051... | lld:pubmed |
| pubmed-article:12034051 | pubmed:meshHeading | pubmed-meshheading:12034051... | lld:pubmed |
| pubmed-article:12034051 | pubmed:meshHeading | pubmed-meshheading:12034051... | lld:pubmed |
| pubmed-article:12034051 | pubmed:meshHeading | pubmed-meshheading:12034051... | lld:pubmed |
| pubmed-article:12034051 | pubmed:meshHeading | pubmed-meshheading:12034051... | lld:pubmed |
| pubmed-article:12034051 | pubmed:meshHeading | pubmed-meshheading:12034051... | lld:pubmed |
| pubmed-article:12034051 | pubmed:meshHeading | pubmed-meshheading:12034051... | lld:pubmed |
| pubmed-article:12034051 | pubmed:meshHeading | pubmed-meshheading:12034051... | lld:pubmed |
| pubmed-article:12034051 | pubmed:year | 2002 | lld:pubmed |
| pubmed-article:12034051 | pubmed:articleTitle | Correlation between morphology of colonies formed by human thyroid tumor cells in collagen gel culture and invasive ability. | lld:pubmed |
| pubmed-article:12034051 | pubmed:affiliation | Department of Otolaryngology, Faculty of Pharmaceutical Sciences, University School of Medicine, Osakasayama, Osaka, Japan. | lld:pubmed |
| pubmed-article:12034051 | pubmed:publicationType | Journal Article | lld:pubmed |
