| pubmed-article:12002703 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:12002703 | lifeskim:mentions | umls-concept:C0006142 | lld:lifeskim |
| pubmed-article:12002703 | lifeskim:mentions | umls-concept:C0677944 | lld:lifeskim |
| pubmed-article:12002703 | lifeskim:mentions | umls-concept:C0205262 | lld:lifeskim |
| pubmed-article:12002703 | pubmed:issue | 3 | lld:pubmed |
| pubmed-article:12002703 | pubmed:dateCreated | 2002-5-10 | lld:pubmed |
| pubmed-article:12002703 | pubmed:abstractText | The purpose of this study was to analyse the occurrence of non-visualisation during preoperative lymphoscintigraphy for sentinel node identification in breast cancer. Preoperative lymphoscintigraphy was performed in 495 clinically node-negative breast cancer patients (501 sentinel node procedures) after injection of technetium-99m nanocolloid. Anterior and prone lateral (hanging breast) planar images were obtained a few minutes and 4 h after injection. The sentinel node was intraoperatively identified with the aid of patent blue dye and a gamma-ray detection probe. A sentinel node was visualised on the 4-h images in 449 of 501 procedures (90%). This visualisation rate improved from 76% to 94% during the study period. Delayed imaging (5-23 h) in 19 patients whose sentinel nodes failed to show, resulted in visualisation in four of them. A repeat injection of radiocolloid in 11 patients revealed a sentinel node in six. In the end, the visualisation rate was 92%. The sentinel node was surgically retrieved in 24 of the remaining 42 patients with non-visualisation (57%). Sentinel nodes that were visualised were tumour-positive in 38% and non-visualised sentinel nodes were involved in 50% (chi2, P=0.17). In a multivariate regression analysis, scintigraphic non-visualisation was independently associated with increased patient age (P<0.001), decreased tracer dose (P<0.001) and increased number of tumour-positive lymph nodes (P=0.013). The use of a sufficient amount of radioactivity (at least 100 MBq) is recommended for lymphatic mapping in breast cancer, especially in elderly women. Delayed imaging and re-injection of the radioactive tracer increase the visualisation rate. The non-visualised sentinel node can be identified intraoperatively in more than half of the patients. | lld:pubmed |
| pubmed-article:12002703 | pubmed:language | eng | lld:pubmed |
| pubmed-article:12002703 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12002703 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:12002703 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12002703 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12002703 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:12002703 | pubmed:month | Mar | lld:pubmed |
| pubmed-article:12002703 | pubmed:issn | 1619-7070 | lld:pubmed |
| pubmed-article:12002703 | pubmed:author | pubmed-author:HoefnagelC... | lld:pubmed |
| pubmed-article:12002703 | pubmed:author | pubmed-author:Valdés... | lld:pubmed |
| pubmed-article:12002703 | pubmed:author | pubmed-author:NiewegO EOE | lld:pubmed |
| pubmed-article:12002703 | pubmed:author | pubmed-author:van... | lld:pubmed |
| pubmed-article:12002703 | pubmed:author | pubmed-author:TanisP JPJ | lld:pubmed |
| pubmed-article:12002703 | pubmed:author | pubmed-author:KroonB B RBB | lld:pubmed |
| pubmed-article:12002703 | pubmed:author | pubmed-author:RutgersE J... | lld:pubmed |
| pubmed-article:12002703 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:12002703 | pubmed:volume | 29 | lld:pubmed |
| pubmed-article:12002703 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:12002703 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:12002703 | pubmed:pagination | 305-11 | lld:pubmed |
| pubmed-article:12002703 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:12002703 | pubmed:meshHeading | pubmed-meshheading:12002703... | lld:pubmed |
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| pubmed-article:12002703 | pubmed:meshHeading | pubmed-meshheading:12002703... | lld:pubmed |
| pubmed-article:12002703 | pubmed:year | 2002 | lld:pubmed |
| pubmed-article:12002703 | pubmed:articleTitle | The hidden sentinel node in breast cancer. | lld:pubmed |
| pubmed-article:12002703 | pubmed:affiliation | Department of Surgery, The Netherlands Cancer Institute, Amsterdam. ptanis@nki.nl | lld:pubmed |
| pubmed-article:12002703 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:12002703 | pubmed:publicationType | Clinical Trial | lld:pubmed |
| pubmed-article:12002703 | pubmed:publicationType | Comparative Study | lld:pubmed |
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