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pubmed-article:11915065pubmed:abstractTextWe tested the hypothesis that the duration of cutaneous anesthesia elicited by the permanently charged compound N-phenylethyl lidocaine (tonicaine) would be longer than that elicited by its parent structure, lidocaine, and that it would be less affected by epinephrine (epi), after subcutaneous injection in rats, as a model for infiltration anesthesia.lld:pubmed
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pubmed-article:11915065pubmed:dateRevised2007-11-14lld:pubmed
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pubmed-article:11915065pubmed:articleTitleUse of a charged lidocaine derivative, tonicaine, for prolonged infiltration anesthesia.lld:pubmed
pubmed-article:11915065pubmed:affiliationDepartment of Anesthesiology, Tufts University School of Medicine and New England Medical Center, Boston, Massachusetts.lld:pubmed
pubmed-article:11915065pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:11915065pubmed:publicationTypeResearch Support, U.S. Gov't, P.H.S.lld:pubmed