| pubmed-article:1184965 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:1184965 | lifeskim:mentions | umls-concept:C0024264 | lld:lifeskim |
| pubmed-article:1184965 | lifeskim:mentions | umls-concept:C1704632 | lld:lifeskim |
| pubmed-article:1184965 | lifeskim:mentions | umls-concept:C0871261 | lld:lifeskim |
| pubmed-article:1184965 | lifeskim:mentions | umls-concept:C1318468 | lld:lifeskim |
| pubmed-article:1184965 | lifeskim:mentions | umls-concept:C0036849 | lld:lifeskim |
| pubmed-article:1184965 | lifeskim:mentions | umls-concept:C2911692 | lld:lifeskim |
| pubmed-article:1184965 | lifeskim:mentions | umls-concept:C1706817 | lld:lifeskim |
| pubmed-article:1184965 | lifeskim:mentions | umls-concept:C0439801 | lld:lifeskim |
| pubmed-article:1184965 | lifeskim:mentions | umls-concept:C1533691 | lld:lifeskim |
| pubmed-article:1184965 | lifeskim:mentions | umls-concept:C1511636 | lld:lifeskim |
| pubmed-article:1184965 | lifeskim:mentions | umls-concept:C0079411 | lld:lifeskim |
| pubmed-article:1184965 | lifeskim:mentions | umls-concept:C0521115 | lld:lifeskim |
| pubmed-article:1184965 | lifeskim:mentions | umls-concept:C0002131 | lld:lifeskim |
| pubmed-article:1184965 | pubmed:issue | 6 | lld:pubmed |
| pubmed-article:1184965 | pubmed:dateCreated | 1976-2-2 | lld:pubmed |
| pubmed-article:1184965 | pubmed:abstractText | The conditions for generation of simultaneous and independent cytotoxic lymphocyte (CL) responses to each of two sets of alloantigens of limited cross-reactivity by mouse spleen cells in vitro have been investigated. Responder spleen cells were incubated with mitomycin C-treated C57BL/6 (H-2b) or DBA/2 (H-2d) stimulator spleen cells and day 5 CL responses were assayed with 51Cr-labeled EL-4 leukemia (H-2b) and P815 mastocytoma (H-2d) as target cells. Spleen cells from mice of the various H-2 haplotypes tested differed greatly in their ability to develop specific CL responses against alloantigens on the stimulator spleen cells and in the degree of cross-reactive cytotoxic activity against target cells bearing alloantigens not present on the stimulator spleen cells. In contrast to the other strains examined, DBA/1 (H-2q) spleen cells developed specific CL responses to either H-2b or H-2d alloantigens without exhibiting significant cross-reactive activity on the inappropriate target cell. The CL responses to H-2b and H-2d alloantigens by DBA/1 spleen cells were comparable in magnitude and had similar stimulator cell-dose requirements. Further, DBA/1 spleen cells developed CL responses of normal magnitude simultaneously against both target cells when incubated with both mitomycin C-treated C57BL/6 and DBA/2 stimulator cells. | lld:pubmed |
| pubmed-article:1184965 | pubmed:language | eng | lld:pubmed |
| pubmed-article:1184965 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1184965 | pubmed:citationSubset | AIM | lld:pubmed |
| pubmed-article:1184965 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1184965 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1184965 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:1184965 | pubmed:month | Dec | lld:pubmed |
| pubmed-article:1184965 | pubmed:issn | 0022-1767 | lld:pubmed |
| pubmed-article:1184965 | pubmed:author | pubmed-author:PierceC WCW | lld:pubmed |
| pubmed-article:1184965 | pubmed:author | pubmed-author:PeavyD LDL | lld:pubmed |
| pubmed-article:1184965 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:1184965 | pubmed:volume | 115 | lld:pubmed |
| pubmed-article:1184965 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:1184965 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:1184965 | pubmed:pagination | 1515-20 | lld:pubmed |
| pubmed-article:1184965 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:1184965 | pubmed:meshHeading | pubmed-meshheading:1184965-... | lld:pubmed |
| pubmed-article:1184965 | pubmed:meshHeading | pubmed-meshheading:1184965-... | lld:pubmed |
| pubmed-article:1184965 | pubmed:meshHeading | pubmed-meshheading:1184965-... | lld:pubmed |
| pubmed-article:1184965 | pubmed:meshHeading | pubmed-meshheading:1184965-... | lld:pubmed |
| pubmed-article:1184965 | pubmed:meshHeading | pubmed-meshheading:1184965-... | lld:pubmed |
| pubmed-article:1184965 | pubmed:meshHeading | pubmed-meshheading:1184965-... | lld:pubmed |
| pubmed-article:1184965 | pubmed:meshHeading | pubmed-meshheading:1184965-... | lld:pubmed |
| pubmed-article:1184965 | pubmed:meshHeading | pubmed-meshheading:1184965-... | lld:pubmed |
| pubmed-article:1184965 | pubmed:meshHeading | pubmed-meshheading:1184965-... | lld:pubmed |
| pubmed-article:1184965 | pubmed:meshHeading | pubmed-meshheading:1184965-... | lld:pubmed |
| pubmed-article:1184965 | pubmed:meshHeading | pubmed-meshheading:1184965-... | lld:pubmed |
| pubmed-article:1184965 | pubmed:meshHeading | pubmed-meshheading:1184965-... | lld:pubmed |
| pubmed-article:1184965 | pubmed:meshHeading | pubmed-meshheading:1184965-... | lld:pubmed |
| pubmed-article:1184965 | pubmed:meshHeading | pubmed-meshheading:1184965-... | lld:pubmed |
| pubmed-article:1184965 | pubmed:year | 1975 | lld:pubmed |
| pubmed-article:1184965 | pubmed:articleTitle | Cell-mediated immune responses in vitro. II. Simultaneous generation of cytotoxic lymphocyte responses to two sets of alloantigens of limited cross-reactivity. | lld:pubmed |
| pubmed-article:1184965 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:1184965 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1184965 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1184965 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1184965 | lld:pubmed |
