pubmed-article:11755417 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:11755417 | lifeskim:mentions | umls-concept:C0043227 | lld:lifeskim |
pubmed-article:11755417 | lifeskim:mentions | umls-concept:C0332307 | lld:lifeskim |
pubmed-article:11755417 | lifeskim:mentions | umls-concept:C0036111 | lld:lifeskim |
pubmed-article:11755417 | lifeskim:mentions | umls-concept:C0033684 | lld:lifeskim |
pubmed-article:11755417 | lifeskim:mentions | umls-concept:C1327616 | lld:lifeskim |
pubmed-article:11755417 | lifeskim:mentions | umls-concept:C1659441 | lld:lifeskim |
pubmed-article:11755417 | pubmed:issue | 14-15 | lld:pubmed |
pubmed-article:11755417 | pubmed:dateCreated | 2001-12-28 | lld:pubmed |
pubmed-article:11755417 | pubmed:abstractText | Upon contact with intestinal epithelial cells, Salmonella enterica serovar spp. inject a set of bacterial proteins into host cells via the bacterial SPI-1 type III secretion system. SopE, SopE2 and SopB, activate CDC42 and Rac to initiate actin cytoskeleton rearrangements. SipA and SipC, two Salmonella actin-binding proteins, directly modulate host actin dynamics to facilitate bacterial uptake. SptP promotes the recovery of the actin cytoskeleton rearrangements by antagonizing CDC42 and Rac. Therefore, Salmonella-induced reversible actin cytoskeleton rearrangements are the result of two coordinated steps: (i) stimulation of host signal transduction to indirectly promote actin rearrangements and (ii) direct modulation of actin dynamics. | lld:pubmed |
pubmed-article:11755417 | pubmed:language | eng | lld:pubmed |
pubmed-article:11755417 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:11755417 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:11755417 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:11755417 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:11755417 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:11755417 | pubmed:issn | 1286-4579 | lld:pubmed |
pubmed-article:11755417 | pubmed:author | pubmed-author:GalánJJ | lld:pubmed |
pubmed-article:11755417 | pubmed:author | pubmed-author:ZhouDD | lld:pubmed |
pubmed-article:11755417 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:11755417 | pubmed:volume | 3 | lld:pubmed |
pubmed-article:11755417 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:11755417 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:11755417 | pubmed:pagination | 1293-8 | lld:pubmed |
pubmed-article:11755417 | pubmed:dateRevised | 2005-11-16 | lld:pubmed |
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pubmed-article:11755417 | pubmed:articleTitle | Salmonella entry into host cells: the work in concert of type III secreted effector proteins. | lld:pubmed |
pubmed-article:11755417 | pubmed:affiliation | Department of Biological Sciences, Purdue University, West Lafayette, IN 47907, USA. zhoud@purdue.edu | lld:pubmed |
pubmed-article:11755417 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:11755417 | pubmed:publicationType | Review | lld:pubmed |
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