pubmed-article:11744231 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:11744231 | lifeskim:mentions | umls-concept:C1257890 | lld:lifeskim |
pubmed-article:11744231 | lifeskim:mentions | umls-concept:C0025914 | lld:lifeskim |
pubmed-article:11744231 | lifeskim:mentions | umls-concept:C0026809 | lld:lifeskim |
pubmed-article:11744231 | lifeskim:mentions | umls-concept:C0206529 | lld:lifeskim |
pubmed-article:11744231 | lifeskim:mentions | umls-concept:C2610415 | lld:lifeskim |
pubmed-article:11744231 | lifeskim:mentions | umls-concept:C0205263 | lld:lifeskim |
pubmed-article:11744231 | lifeskim:mentions | umls-concept:C1519355 | lld:lifeskim |
pubmed-article:11744231 | pubmed:issue | 3 | lld:pubmed |
pubmed-article:11744231 | pubmed:dateCreated | 2001-12-17 | lld:pubmed |
pubmed-article:11744231 | pubmed:abstractText | We studied the roles of mGlu2/3 receptors (mGlu2/3) in glutamatergic transmission at corticostriatal synapses in mice brain slices. Perfusion of the selective mGlu2/3 agonists LY354740 and L-CCG1 caused the long term depression (LTD) of evoked synaptic responses. Photonic and electronic microscopy showed mGlu2/3 on axonal fibers and glial processes but not on striatal dendrites. mGlu2/3-LTD was independent of synaptic activity and insensitive to specific antagonists of dopamine D1, D2, GABA(B), N-methyl-D-aspartate or adenosine A1 receptors. Manipulation of the cAMP/protein kinase A cascade had no effect on the mGlu2/3-LTD. In contrast, MEK1-2 inhibitors reduced both mGlu2/3 initial depression and LTD suggesting the involvement of the mitogen activated kinase pathway in mGlu2/3-LTD. | lld:pubmed |
pubmed-article:11744231 | pubmed:language | eng | lld:pubmed |
pubmed-article:11744231 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:11744231 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:11744231 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:11744231 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:11744231 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:11744231 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:11744231 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:11744231 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:11744231 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:11744231 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:11744231 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:11744231 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:11744231 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:11744231 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:11744231 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:11744231 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:11744231 | pubmed:month | Dec | lld:pubmed |
pubmed-article:11744231 | pubmed:issn | 0304-3940 | lld:pubmed |
pubmed-article:11744231 | pubmed:author | pubmed-author:BockaertJJ | lld:pubmed |
pubmed-article:11744231 | pubmed:author | pubmed-author:AlonsoGG | lld:pubmed |
pubmed-article:11744231 | pubmed:author | pubmed-author:KahnLL | lld:pubmed |
pubmed-article:11744231 | pubmed:author | pubmed-author:ManzoniO JOJ | lld:pubmed |
pubmed-article:11744231 | pubmed:author | pubmed-author:RobbeDD | lld:pubmed |
pubmed-article:11744231 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:11744231 | pubmed:day | 28 | lld:pubmed |
pubmed-article:11744231 | pubmed:volume | 316 | lld:pubmed |
pubmed-article:11744231 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:11744231 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:11744231 | pubmed:pagination | 178-82 | lld:pubmed |
pubmed-article:11744231 | pubmed:dateRevised | 2009-11-19 | lld:pubmed |
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pubmed-article:11744231 | pubmed:year | 2001 | lld:pubmed |
pubmed-article:11744231 | pubmed:articleTitle | Group 2 metabotropic glutamate receptors induced long term depression in mouse striatal slices. | lld:pubmed |
pubmed-article:11744231 | pubmed:affiliation | CNRS UPR 9023, 141, Rue de la Cardonille, 34094 Montpellier Cedex 05, France. | lld:pubmed |
pubmed-article:11744231 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:11744231 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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