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pubmed-article:11734231pubmed:abstractTextPegvisomant is a new growth hormone receptor antagonist that improves symptoms and normalises insulin-like growth factor-1 (IGF-1) in a high proportion of patients with acromegaly treated for up to 12 weeks. We assessed the effects of pegvisomant in 160 patients with acromegaly treated for an average of 425 days.lld:pubmed
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pubmed-article:11734231pubmed:articleTitleLong-term treatment of acromegaly with pegvisomant, a growth hormone receptor antagonist.lld:pubmed
pubmed-article:11734231pubmed:affiliationErasmus Medical Centre Rotterdam, 40 Dr Molewaterplein, 3015 GD, Rotterdam, Netherlands. vanderlely@inw3.azr.nllld:pubmed
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