| pubmed-article:11733137 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:11733137 | lifeskim:mentions | umls-concept:C0030498 | lld:lifeskim |
| pubmed-article:11733137 | lifeskim:mentions | umls-concept:C0023675 | lld:lifeskim |
| pubmed-article:11733137 | lifeskim:mentions | umls-concept:C0015576 | lld:lifeskim |
| pubmed-article:11733137 | lifeskim:mentions | umls-concept:C0243045 | lld:lifeskim |
| pubmed-article:11733137 | lifeskim:mentions | umls-concept:C0033640 | lld:lifeskim |
| pubmed-article:11733137 | lifeskim:mentions | umls-concept:C1521970 | lld:lifeskim |
| pubmed-article:11733137 | lifeskim:mentions | umls-concept:C0017262 | lld:lifeskim |
| pubmed-article:11733137 | lifeskim:mentions | umls-concept:C1514562 | lld:lifeskim |
| pubmed-article:11733137 | lifeskim:mentions | umls-concept:C0085328 | lld:lifeskim |
| pubmed-article:11733137 | lifeskim:mentions | umls-concept:C0683941 | lld:lifeskim |
| pubmed-article:11733137 | lifeskim:mentions | umls-concept:C0679622 | lld:lifeskim |
| pubmed-article:11733137 | lifeskim:mentions | umls-concept:C2700640 | lld:lifeskim |
| pubmed-article:11733137 | lifeskim:mentions | umls-concept:C0205314 | lld:lifeskim |
| pubmed-article:11733137 | lifeskim:mentions | umls-concept:C2911684 | lld:lifeskim |
| pubmed-article:11733137 | lifeskim:mentions | umls-concept:C0185117 | lld:lifeskim |
| pubmed-article:11733137 | pubmed:issue | 2 | lld:pubmed |
| pubmed-article:11733137 | pubmed:dateCreated | 2001-12-4 | lld:pubmed |
| pubmed-article:11733137 | pubmed:databankReference | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11733137 | pubmed:abstractText | The TaCRK3 gene from the bovine apicomplexan parasite Theileria annulata, encodes a 46 kDa polypeptide with strong homology to the eukaryotic family of cyclin-dependent kinases. TaCRK3 does not show significant alignment with any particular CDK group, other than the Pfmrk kinases from the related apicomplexans Plasmodium falciparum and Plasmodium yoelii. It has a putative bipartite nuclear localization signal and is located to parasite nuclei by IFAT. Protein levels are constitutive throughout differentiation of the intra-lymphocytic macroschizont. This contrasts with the expression pattern of TaCRK2 (Kinnaird et al., 1996, Mol. Microbiol., 22, 293-302) which is closely related to the eukaryotic CDK1 /2 families involved in regulation of cell cycle progression. TaCRK2 is also located to the parasite nuclei but has no nuclear localization signal and exhibits transient up-regulation in protein levels during mid-merogony. However compared to TaCRK3, it shows down-regulation near the end of merogony. We predict that TaCRK3 may have a role in regulation of gene transcription while TaCRK2 is more likely to be involved in control of parasite nuclear division. | lld:pubmed |
| pubmed-article:11733137 | pubmed:language | eng | lld:pubmed |
| pubmed-article:11733137 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11733137 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:11733137 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11733137 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11733137 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11733137 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11733137 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11733137 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11733137 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11733137 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11733137 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:11733137 | pubmed:month | Nov | lld:pubmed |
| pubmed-article:11733137 | pubmed:issn | 0378-1119 | lld:pubmed |
| pubmed-article:11733137 | pubmed:author | pubmed-author:TaitAA | lld:pubmed |
| pubmed-article:11733137 | pubmed:author | pubmed-author:LoganMM | lld:pubmed |
| pubmed-article:11733137 | pubmed:author | pubmed-author:LangsletJJ | lld:pubmed |
| pubmed-article:11733137 | pubmed:author | pubmed-author:KinnairdJJ | lld:pubmed |
| pubmed-article:11733137 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:11733137 | pubmed:day | 28 | lld:pubmed |
| pubmed-article:11733137 | pubmed:volume | 279 | lld:pubmed |
| pubmed-article:11733137 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:11733137 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:11733137 | pubmed:pagination | 127-35 | lld:pubmed |
| pubmed-article:11733137 | pubmed:dateRevised | 2009-11-19 | lld:pubmed |
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| pubmed-article:11733137 | pubmed:meshHeading | pubmed-meshheading:11733137... | lld:pubmed |
| pubmed-article:11733137 | pubmed:meshHeading | pubmed-meshheading:11733137... | lld:pubmed |
| pubmed-article:11733137 | pubmed:meshHeading | pubmed-meshheading:11733137... | lld:pubmed |
| pubmed-article:11733137 | pubmed:meshHeading | pubmed-meshheading:11733137... | lld:pubmed |
| pubmed-article:11733137 | pubmed:year | 2001 | lld:pubmed |
| pubmed-article:11733137 | pubmed:articleTitle | TaCRK3 encodes a novel Theileria annulata protein kinase with motifs characteristic of the family of eukaryotic cyclin dependent kinases: a comparative analysis of its expression with TaCRK2 during the parasite life cycle. | lld:pubmed |
| pubmed-article:11733137 | pubmed:affiliation | Department of Veterinary Parasitology, Glasgow University, Bearsden Road, Glasgow G61 1QH, UK. j.kinnaird@vet.gla.ac.uk | lld:pubmed |
| pubmed-article:11733137 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:11733137 | pubmed:publicationType | Comparative Study | lld:pubmed |
| pubmed-article:11733137 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
