| pubmed-article:11716816 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:11716816 | lifeskim:mentions | umls-concept:C0009170 | lld:lifeskim |
| pubmed-article:11716816 | lifeskim:mentions | umls-concept:C0002658 | lld:lifeskim |
| pubmed-article:11716816 | lifeskim:mentions | umls-concept:C0087140 | lld:lifeskim |
| pubmed-article:11716816 | lifeskim:mentions | umls-concept:C0175173 | lld:lifeskim |
| pubmed-article:11716816 | lifeskim:mentions | umls-concept:C0007461 | lld:lifeskim |
| pubmed-article:11716816 | lifeskim:mentions | umls-concept:C0028633 | lld:lifeskim |
| pubmed-article:11716816 | lifeskim:mentions | umls-concept:C0085732 | lld:lifeskim |
| pubmed-article:11716816 | lifeskim:mentions | umls-concept:C1515670 | lld:lifeskim |
| pubmed-article:11716816 | lifeskim:mentions | umls-concept:C0205263 | lld:lifeskim |
| pubmed-article:11716816 | lifeskim:mentions | umls-concept:C0683581 | lld:lifeskim |
| pubmed-article:11716816 | pubmed:issue | 1-2 | lld:pubmed |
| pubmed-article:11716816 | pubmed:dateCreated | 2001-11-21 | lld:pubmed |
| pubmed-article:11716816 | pubmed:abstractText | We reported previously that environmental novelty enhances the acute psychomotor activating effects of amphetamine, its ability to induce behavioral sensitization, and its ability to induce c-fos mRNA in the striatum and other structures, relative to when amphetamine is given in the home cage. The purpose of the present experiment was 2-fold: to determine (1) whether environmental novelty has a similar effect on the ability of cocaine to induce c-fos mRNA, and (2) whether this effect is seen in neurologically-intact rats (in previous experiments we studied the intact hemisphere of rats with a unilateral 6-OHDA lesion). In the dorsal portion of the caudate putamen, core and shell of the nucleus accumbens, and in several cortical regions, both amphetamine (1.5 mg/kg) and cocaine (15 mg/kg) induced higher levels of c-fos mRNA expression when administered in a novel environment, relative to when they were administered in the home cage. The ability of environmental context to modulate psychostimulant drug-induced immediate early gene expression may be related to its ability to modulate forms of drug experience-dependent plasticity, such as behavioral sensitization. | lld:pubmed |
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| pubmed-article:11716816 | pubmed:language | eng | lld:pubmed |
| pubmed-article:11716816 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11716816 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:11716816 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:11716816 | pubmed:month | Nov | lld:pubmed |
| pubmed-article:11716816 | pubmed:issn | 0006-8993 | lld:pubmed |
| pubmed-article:11716816 | pubmed:author | pubmed-author:RobinsonT ETE | lld:pubmed |
| pubmed-article:11716816 | pubmed:author | pubmed-author:WatsonS JSJ | lld:pubmed |
| pubmed-article:11716816 | pubmed:author | pubmed-author:AkilHH | lld:pubmed |
| pubmed-article:11716816 | pubmed:author | pubmed-author:KIMS KSK | lld:pubmed |
| pubmed-article:11716816 | pubmed:author | pubmed-author:BadianeMM | lld:pubmed |
| pubmed-article:11716816 | pubmed:author | pubmed-author:UslanerJJ | lld:pubmed |
| pubmed-article:11716816 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:11716816 | pubmed:day | 30 | lld:pubmed |
| pubmed-article:11716816 | pubmed:volume | 920 | lld:pubmed |
| pubmed-article:11716816 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:11716816 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:11716816 | pubmed:pagination | 106-16 | lld:pubmed |
| pubmed-article:11716816 | pubmed:dateRevised | 2007-11-14 | lld:pubmed |
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| pubmed-article:11716816 | pubmed:year | 2001 | lld:pubmed |
| pubmed-article:11716816 | pubmed:articleTitle | Environmental context modulates the ability of cocaine and amphetamine to induce c-fos mRNA expression in the neocortex, caudate nucleus, and nucleus accumbens. | lld:pubmed |
| pubmed-article:11716816 | pubmed:affiliation | Biopsychology Programs, Department of Psychology, University of Michigan, East Hall, 525 East University Street, Ann Arbor, MI 48019-1109, USA. | lld:pubmed |
| pubmed-article:11716816 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:11716816 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
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