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pubmed-article:11711842pubmed:abstractTextRS-Betaxolol (equimolar R- and S- isomers) lowers intraocular pressure and dilates precontracted retinal and posterior ciliary arteries in vitro. Betaxolol's vasorelaxant effect is thought to involve the inhibition of calcium influx into vascular smooth muscle and is unrelated to its stereoselective beta-adrenergic blocking action. The authors assessed the vasodilatory effect of RS-betaxolol on different diameters of bovine retinal arterioles and venules, and these responses were compared with the responses induced by R- and S-betaxolol isomers in vitro.lld:pubmed
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pubmed-article:11711842pubmed:articleTitleVasorelaxant effects of racemic betaxolol and its R- and S- isomers on bovine retinal vessels.lld:pubmed
pubmed-article:11711842pubmed:affiliationDepartment of Ophthalmology and Visual Science, School of Medicine at University of Louisville, Louisville, Kentucky 40202, USA.lld:pubmed
pubmed-article:11711842pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:11711842pubmed:publicationTypeComparative Studylld:pubmed
pubmed-article:11711842pubmed:publicationTypeResearch Support, Non-U.S. Gov'tlld:pubmed
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