Statements in which the resource exists.
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pubmed-article:11576620pubmed:dateCreated2001-9-28lld:pubmed
pubmed-article:11576620pubmed:abstractTextKyotorphin (KTP, H-Tyr-Arg-OH) was covalently bonded with hydrocortisone or estrone to form the corresponding hydrocortisone-21-O-yl-succinyl-Tyr-ArgOH or estrone-3-O-yl-acyl-Tyr-Arg-OH. Their analgesic activities were investigated using the tail flick test. The potency of the two linkers were significantly higher than that of KTP and the mixture of KTP and hydrocortisone or estrone in the CNS and/or the periphery administration.lld:pubmed
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pubmed-article:11576620pubmed:year2001lld:pubmed
pubmed-article:11576620pubmed:articleTitleSynthesis and analgesic effects of kyotorphin-steroid linkers.lld:pubmed
pubmed-article:11576620pubmed:affiliationCollege of Pharmaceutical Sciences, Peking University, Beijing 100083, P.R. China.lld:pubmed
pubmed-article:11576620pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:11576620pubmed:publicationTypeResearch Support, Non-U.S. Gov'tlld:pubmed