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pubmed-article:11553200pubmed:abstractTextLow birth weight may predispose to later insulin resistance and hyperinsulinaemia, but the pathophysiological mechanisms are unclear. The perinatal endocrine situation may play an important role, but has been little studied. Children of mothers with diabetes during pregnancy are an important risk population for later insulin resistance and hyperinsulinaemia. We therefore examined relationships between birth weight, insulin and insulin resistance at birth, and insulin secretion and insulin resistance in infancy in these children.lld:pubmed
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pubmed-article:11553200pubmed:articleTitlePerinatal 'programming' of insulin resistance in childhood: critical impact of neonatal insulin and low birth weight in a risk population.lld:pubmed
pubmed-article:11553200pubmed:affiliationInstitute of Experimental Endocrinology, Humboldt University Medical School (Charité), Berlin, Germany.lld:pubmed
pubmed-article:11553200pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:11553200pubmed:publicationTypeResearch Support, Non-U.S. Gov'tlld:pubmed
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