| pubmed-article:11531967 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:11531967 | lifeskim:mentions | umls-concept:C0015176 | lld:lifeskim |
| pubmed-article:11531967 | lifeskim:mentions | umls-concept:C0031437 | lld:lifeskim |
| pubmed-article:11531967 | lifeskim:mentions | umls-concept:C1418544 | lld:lifeskim |
| pubmed-article:11531967 | lifeskim:mentions | umls-concept:C0034037 | lld:lifeskim |
| pubmed-article:11531967 | lifeskim:mentions | umls-concept:C1704324 | lld:lifeskim |
| pubmed-article:11531967 | lifeskim:mentions | umls-concept:C0038951 | lld:lifeskim |
| pubmed-article:11531967 | lifeskim:mentions | umls-concept:C0936012 | lld:lifeskim |
| pubmed-article:11531967 | pubmed:issue | 1 | lld:pubmed |
| pubmed-article:11531967 | pubmed:dateCreated | 2001-9-4 | lld:pubmed |
| pubmed-article:11531967 | pubmed:abstractText | The objective of the present study was to review published surveys on allelic frequencies S and Z in European populations to evaluate the validity of the reported data. More than a hundred studies on the topic, published since 1965 until 2000, were retrieved by Medline, Index Medicus and bibliographic references consultation. The criteria for studies selection were: 1) sample size> or =250 individuals; 2) alpha-1-antitrypsin phenotype determination performed by means of crossed antigen-antibody or isoelectric focusing in polyacrylamide gels; 3) PI type determination performed without any previous screening procedure; 4) S and Z 95% confidence interval (CI) of the reported outcomes with a calculated coefficient of variation <42.3 for S and <95.8 for Z; 5) S and Z 95% CI of the reported outcomes comprised within 95% CI limits of comparative hypothetical surveys designed with the same sample size of the questioned surveys and the highest/lowest frequencies accepted for a specific area, according to the figures of isogen boundary maps. Seventy studies comply with the five established criteria for analysis. According to the data of the selected studies, a geographical distribution on S and Z gene frequencies in Europe is proposed. | lld:pubmed |
| pubmed-article:11531967 | pubmed:language | eng | lld:pubmed |
| pubmed-article:11531967 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11531967 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:11531967 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11531967 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:11531967 | pubmed:month | Jul | lld:pubmed |
| pubmed-article:11531967 | pubmed:issn | 0009-9163 | lld:pubmed |
| pubmed-article:11531967 | pubmed:author | pubmed-author:BlancoII | lld:pubmed |
| pubmed-article:11531967 | pubmed:author | pubmed-author:FernándezEE | lld:pubmed |
| pubmed-article:11531967 | pubmed:author | pubmed-author:BustilloE FEF | lld:pubmed |
| pubmed-article:11531967 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:11531967 | pubmed:volume | 60 | lld:pubmed |
| pubmed-article:11531967 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:11531967 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:11531967 | pubmed:pagination | 31-41 | lld:pubmed |
| pubmed-article:11531967 | pubmed:dateRevised | 2007-11-15 | lld:pubmed |
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| pubmed-article:11531967 | pubmed:meshHeading | pubmed-meshheading:11531967... | lld:pubmed |
| pubmed-article:11531967 | pubmed:meshHeading | pubmed-meshheading:11531967... | lld:pubmed |
| pubmed-article:11531967 | pubmed:meshHeading | pubmed-meshheading:11531967... | lld:pubmed |
| pubmed-article:11531967 | pubmed:meshHeading | pubmed-meshheading:11531967... | lld:pubmed |
| pubmed-article:11531967 | pubmed:meshHeading | pubmed-meshheading:11531967... | lld:pubmed |
| pubmed-article:11531967 | pubmed:year | 2001 | lld:pubmed |
| pubmed-article:11531967 | pubmed:articleTitle | Alpha-1-antitrypsin PI phenotypes S and Z in Europe: an analysis of the published surveys. | lld:pubmed |
| pubmed-article:11531967 | pubmed:affiliation | Respiratory Unit, Hospital Valle del Nalón, Asturias, Spain. iblanco@hvnl.insalud.es | lld:pubmed |
| pubmed-article:11531967 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:11531967 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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