| pubmed-article:11369174 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:11369174 | lifeskim:mentions | umls-concept:C0043251 | lld:lifeskim |
| pubmed-article:11369174 | lifeskim:mentions | umls-concept:C0543467 | lld:lifeskim |
| pubmed-article:11369174 | lifeskim:mentions | umls-concept:C0034721 | lld:lifeskim |
| pubmed-article:11369174 | lifeskim:mentions | umls-concept:C0034693 | lld:lifeskim |
| pubmed-article:11369174 | lifeskim:mentions | umls-concept:C0242692 | lld:lifeskim |
| pubmed-article:11369174 | lifeskim:mentions | umls-concept:C0021641 | lld:lifeskim |
| pubmed-article:11369174 | lifeskim:mentions | umls-concept:C0007004 | lld:lifeskim |
| pubmed-article:11369174 | lifeskim:mentions | umls-concept:C0441472 | lld:lifeskim |
| pubmed-article:11369174 | lifeskim:mentions | umls-concept:C1280500 | lld:lifeskim |
| pubmed-article:11369174 | lifeskim:mentions | umls-concept:C0204695 | lld:lifeskim |
| pubmed-article:11369174 | pubmed:issue | 4 | lld:pubmed |
| pubmed-article:11369174 | pubmed:dateCreated | 2001-5-22 | lld:pubmed |
| pubmed-article:11369174 | pubmed:abstractText | Metabolic stress after surgery is associated with peripheral insulin resistance. Recent studies have suggested that preoperative glucose can ameliorate postoperative decreases in insulin-stimulated glucose disposal. In the present experiments, we used a bowel-resection model of surgical trauma to test the hypothesis that elevations of serum insulin induced by preoperative oral glucose or ad libitum feeding affects postoperative insulin-stimulated glucose uptake in skeletal muscle. Insulin-stimulated glucose transport was measured in vitro in soleus muscles after surgical trauma in fasted rats given oral glucose or water before surgery. Insulin-stimulated glucose transport was also assessed in vitro in fasted or fed traumatized rats and non-traumatized control animals. In addition, stress hormones (glucagon, corticosterone, and adrenaline) were measured before and after surgical trauma in fasted rats and rats fed ad libitum. In vitro skeletal-muscle insulin sensitivity and responsiveness were reduced postoperatively in fasted animals that received oral glucose loads before bowel resections and in rats fed ad libitum or fasted before surgery versus non-traumatized rats (all P < 0.05). Stress-hormone concentrations after trauma did not differ between fed and fasted animals. In the current study, insulin sensitivity and responsiveness were reduced in isolated skeletal muscles after bowel resection, but neither preoperative glucose supplementation nor free intake of mixed nutrients ameliorated the development of postoperative insulin resistance. | lld:pubmed |
| pubmed-article:11369174 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11369174 | pubmed:language | eng | lld:pubmed |
| pubmed-article:11369174 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11369174 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:11369174 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11369174 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11369174 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11369174 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11369174 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:11369174 | pubmed:month | Apr | lld:pubmed |
| pubmed-article:11369174 | pubmed:issn | 0899-9007 | lld:pubmed |
| pubmed-article:11369174 | pubmed:author | pubmed-author:IsakssonBB | lld:pubmed |
| pubmed-article:11369174 | pubmed:author | pubmed-author:PermertJJ | lld:pubmed |
| pubmed-article:11369174 | pubmed:author | pubmed-author:HerringtonMM | lld:pubmed |
| pubmed-article:11369174 | pubmed:author | pubmed-author:OstensjøRR | lld:pubmed |
| pubmed-article:11369174 | pubmed:author | pubmed-author:ArneloUU | lld:pubmed |
| pubmed-article:11369174 | pubmed:author | pubmed-author:StrömmerLL | lld:pubmed |
| pubmed-article:11369174 | pubmed:author | pubmed-author:WickbomMM | lld:pubmed |
| pubmed-article:11369174 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:11369174 | pubmed:volume | 17 | lld:pubmed |
| pubmed-article:11369174 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:11369174 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:11369174 | pubmed:pagination | 332-6 | lld:pubmed |
| pubmed-article:11369174 | pubmed:dateRevised | 2011-11-17 | lld:pubmed |
| pubmed-article:11369174 | pubmed:meshHeading | pubmed-meshheading:11369174... | lld:pubmed |
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| pubmed-article:11369174 | pubmed:meshHeading | pubmed-meshheading:11369174... | lld:pubmed |
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| pubmed-article:11369174 | pubmed:meshHeading | pubmed-meshheading:11369174... | lld:pubmed |
| pubmed-article:11369174 | pubmed:meshHeading | pubmed-meshheading:11369174... | lld:pubmed |
| pubmed-article:11369174 | pubmed:meshHeading | pubmed-meshheading:11369174... | lld:pubmed |
| pubmed-article:11369174 | pubmed:meshHeading | pubmed-meshheading:11369174... | lld:pubmed |
| pubmed-article:11369174 | pubmed:meshHeading | pubmed-meshheading:11369174... | lld:pubmed |
| pubmed-article:11369174 | pubmed:meshHeading | pubmed-meshheading:11369174... | lld:pubmed |
| pubmed-article:11369174 | pubmed:year | 2001 | lld:pubmed |
| pubmed-article:11369174 | pubmed:articleTitle | Effect of carbohydrate feeding on insulin action in skeletal muscle after surgical trauma in the rat. | lld:pubmed |
| pubmed-article:11369174 | pubmed:affiliation | Arvid Wretlinds Laboratory for Metabolic and Nutritional Research, Department of Surgery, Karolinska Institute at Huddinge University Hospital, Stockholm, Sweden. lisa.strommer@karo.ki.se | lld:pubmed |
| pubmed-article:11369174 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:11369174 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11369174 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11369174 | lld:pubmed |
