pubmed-article:11367742 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:11367742 | lifeskim:mentions | umls-concept:C0015967 | lld:lifeskim |
pubmed-article:11367742 | lifeskim:mentions | umls-concept:C0021755 | lld:lifeskim |
pubmed-article:11367742 | lifeskim:mentions | umls-concept:C0002302 | lld:lifeskim |
pubmed-article:11367742 | lifeskim:mentions | umls-concept:C0392756 | lld:lifeskim |
pubmed-article:11367742 | lifeskim:mentions | umls-concept:C2603343 | lld:lifeskim |
pubmed-article:11367742 | lifeskim:mentions | umls-concept:C0441712 | lld:lifeskim |
pubmed-article:11367742 | pubmed:issue | 5 | lld:pubmed |
pubmed-article:11367742 | pubmed:dateCreated | 2001-5-22 | lld:pubmed |
pubmed-article:11367742 | pubmed:abstractText | The effect of alpha-melanocyte-stimulating hormone (alpha-MSH) on IL-1 beta-induced fever and release of hypothalamic cAMP was observed in the present work. The results showed that alpha-MSH markedly suppressed febrile response (P < 0.05) and decreased the cAMP content in hypothalamus in response to icv injection of IL-1 beta (P < 0.01). The cAMP content of the medium in which the hypothalamic was incubated for 40 min in the presence of IL-1 beta was significantly increased (P < 0.01). However, this increase action could be prevented by a pretreatment with alpha-MSH. The results indicate that the inhibitory effect of alpha-MSH on the enhanced synthesis and release of cAMP in hypothalamus exposed to IL-1 beta might be one of the mechanisms of suppressing fever induced by IL-1 beta. | lld:pubmed |
pubmed-article:11367742 | pubmed:language | chi | lld:pubmed |
pubmed-article:11367742 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:11367742 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:11367742 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:11367742 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:11367742 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:11367742 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:11367742 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:11367742 | pubmed:month | Oct | lld:pubmed |
pubmed-article:11367742 | pubmed:issn | 0371-0874 | lld:pubmed |
pubmed-article:11367742 | pubmed:author | pubmed-author:WangY PYP | lld:pubmed |
pubmed-article:11367742 | pubmed:author | pubmed-author:LiC JCJ | lld:pubmed |
pubmed-article:11367742 | pubmed:author | pubmed-author:WoodT WTW | lld:pubmed |
pubmed-article:11367742 | pubmed:author | pubmed-author:HuC FCF | lld:pubmed |
pubmed-article:11367742 | pubmed:author | pubmed-author:WangH DHD | lld:pubmed |
pubmed-article:11367742 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:11367742 | pubmed:volume | 50 | lld:pubmed |
pubmed-article:11367742 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:11367742 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:11367742 | pubmed:pagination | 490-4 | lld:pubmed |
pubmed-article:11367742 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
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pubmed-article:11367742 | pubmed:year | 1998 | lld:pubmed |
pubmed-article:11367742 | pubmed:articleTitle | [Studies on the mechanism of alpha-MSH in reducing IL-1 beta-induced fever]. | lld:pubmed |
pubmed-article:11367742 | pubmed:affiliation | Department of Pathophysiology and Institute of Fever Research, Medical College, Jinan University, Guangzhou 510632. | lld:pubmed |
pubmed-article:11367742 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:11367742 | pubmed:publicationType | English Abstract | lld:pubmed |
pubmed-article:11367742 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |