| pubmed-article:11342170 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:11342170 | lifeskim:mentions | umls-concept:C0029246 | lld:lifeskim |
| pubmed-article:11342170 | lifeskim:mentions | umls-concept:C0025255 | lld:lifeskim |
| pubmed-article:11342170 | lifeskim:mentions | umls-concept:C0029259 | lld:lifeskim |
| pubmed-article:11342170 | lifeskim:mentions | umls-concept:C1959616 | lld:lifeskim |
| pubmed-article:11342170 | lifeskim:mentions | umls-concept:C0205485 | lld:lifeskim |
| pubmed-article:11342170 | pubmed:issue | 1-2 | lld:pubmed |
| pubmed-article:11342170 | pubmed:dateCreated | 2001-5-8 | lld:pubmed |
| pubmed-article:11342170 | pubmed:abstractText | Organotin compounds have a broad range of biological activities and are ubiquitous contaminants in the environment. Their toxicity mainly lies in their action on the membrane. In this contribution we study the interaction of tributyltin and triphenyltin with model membranes composed of phosphatidylcholines of different acyl chain lengths using differential scanning calorimetry, (31)P-nuclear magnetic resonance, X-ray diffraction and infrared spectroscopy. Organotin compounds broaden the main gel to liquid-crystalline phase transition, shift the transition temperature to lower values and induce the appearance of a new peak below the main transition peak. These effects are more pronounced in the case of tributyltin and are quantitatively larger as the phosphatidylcholine acyl chain length decreases. Both tributyltin and triphenyltin increase the enthalpy change of the transition in all the phosphatidylcholine systems studied except in dilauroylphosphatidylcholine. Organotin compounds do not affect the macroscopic bilayer organization of the phospholipid but do affect the degree of hydration of its carbonyl moiety. The above evidence supports the idea that organotin compounds are located in the upper part of the phospholipid palisade near the lipid/water interface. | lld:pubmed |
| pubmed-article:11342170 | pubmed:language | eng | lld:pubmed |
| pubmed-article:11342170 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11342170 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:11342170 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11342170 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11342170 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11342170 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11342170 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11342170 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11342170 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11342170 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:11342170 | pubmed:month | Feb | lld:pubmed |
| pubmed-article:11342170 | pubmed:issn | 0006-3002 | lld:pubmed |
| pubmed-article:11342170 | pubmed:author | pubmed-author:OrtizAA | lld:pubmed |
| pubmed-article:11342170 | pubmed:author | pubmed-author:TeruelJ AJA | lld:pubmed |
| pubmed-article:11342170 | pubmed:author | pubmed-author:ArandaF JFJ | lld:pubmed |
| pubmed-article:11342170 | pubmed:author | pubmed-author:ChicanoJ JJJ | lld:pubmed |
| pubmed-article:11342170 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:11342170 | pubmed:day | 9 | lld:pubmed |
| pubmed-article:11342170 | pubmed:volume | 1510 | lld:pubmed |
| pubmed-article:11342170 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:11342170 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:11342170 | pubmed:pagination | 330-41 | lld:pubmed |
| pubmed-article:11342170 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:11342170 | pubmed:meshHeading | pubmed-meshheading:11342170... | lld:pubmed |
| pubmed-article:11342170 | pubmed:meshHeading | pubmed-meshheading:11342170... | lld:pubmed |
| pubmed-article:11342170 | pubmed:meshHeading | pubmed-meshheading:11342170... | lld:pubmed |
| pubmed-article:11342170 | pubmed:meshHeading | pubmed-meshheading:11342170... | lld:pubmed |
| pubmed-article:11342170 | pubmed:meshHeading | pubmed-meshheading:11342170... | lld:pubmed |
| pubmed-article:11342170 | pubmed:meshHeading | pubmed-meshheading:11342170... | lld:pubmed |
| pubmed-article:11342170 | pubmed:meshHeading | pubmed-meshheading:11342170... | lld:pubmed |
| pubmed-article:11342170 | pubmed:meshHeading | pubmed-meshheading:11342170... | lld:pubmed |
| pubmed-article:11342170 | pubmed:meshHeading | pubmed-meshheading:11342170... | lld:pubmed |
| pubmed-article:11342170 | pubmed:meshHeading | pubmed-meshheading:11342170... | lld:pubmed |
| pubmed-article:11342170 | pubmed:meshHeading | pubmed-meshheading:11342170... | lld:pubmed |
| pubmed-article:11342170 | pubmed:year | 2001 | lld:pubmed |
| pubmed-article:11342170 | pubmed:articleTitle | Organotin compounds alter the physical organization of phosphatidylcholine membranes. | lld:pubmed |
| pubmed-article:11342170 | pubmed:affiliation | Departamento de Bioquímica y Biología Molecular A, Facultad de Veterinaria, Universidad de Murcia, Campus de Espinardo, E-30100, Murcia, Spain. | lld:pubmed |
| pubmed-article:11342170 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:11342170 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11342170 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11342170 | lld:pubmed |
