| pubmed-article:11322762 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:11322762 | lifeskim:mentions | umls-concept:C0030705 | lld:lifeskim |
| pubmed-article:11322762 | lifeskim:mentions | umls-concept:C0041455 | lld:lifeskim |
| pubmed-article:11322762 | lifeskim:mentions | umls-concept:C0024432 | lld:lifeskim |
| pubmed-article:11322762 | lifeskim:mentions | umls-concept:C0001511 | lld:lifeskim |
| pubmed-article:11322762 | lifeskim:mentions | umls-concept:C0392756 | lld:lifeskim |
| pubmed-article:11322762 | pubmed:issue | 1 | lld:pubmed |
| pubmed-article:11322762 | pubmed:dateCreated | 2001-4-27 | lld:pubmed |
| pubmed-article:11322762 | pubmed:abstractText | CD36 is an 88-kDa glycoprotein expressed on platelets and monocyte/macrophages (Mphi). CD36 is a multifunctional receptor for collagen, thrombospondin, oxidized low density lipoproteins (LDL), and long-chain fatty acids. The present study was performed to investigate whether CD36 can function as an adhesion molecule which is involved in mediating human macrophages (Mphi) adhesion to type I collagen in vitro. The Mphi of human CD36-deficient as well as normal control subjects were isolated and cultured on the multi-well plates coated with type I collagen, a natural ligand for CD36. Up to 2 h of incubation, the Mphi from CD36-deficient patients showed almost a approximately 55% decrease in adhesion to type I collagen in comparison to those from controls (P < 0.01). However, there was no significant difference in the adhesion thereafter. Furthermore, the addition of antibody against CD36 into the media of control Mphi significantly inhibited the adhesion by approximately 50% (P < 0.05). The addition of oxidized LDL (OxLDL) did not alter adhesion of Mphi from both CD36-deficient and controls. These data suggest that CD36 is involved in the adhesion of Mphi to type I collagen, especially in the early stage of adhesion. | lld:pubmed |
| pubmed-article:11322762 | pubmed:language | eng | lld:pubmed |
| pubmed-article:11322762 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11322762 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:11322762 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11322762 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11322762 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11322762 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11322762 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11322762 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11322762 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11322762 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:11322762 | pubmed:month | Apr | lld:pubmed |
| pubmed-article:11322762 | pubmed:issn | 0006-291X | lld:pubmed |
| pubmed-article:11322762 | pubmed:author | pubmed-author:YamashitaSS | lld:pubmed |
| pubmed-article:11322762 | pubmed:author | pubmed-author:MatsuzawaYY | lld:pubmed |
| pubmed-article:11322762 | pubmed:author | pubmed-author:MatsumotoKK | lld:pubmed |
| pubmed-article:11322762 | pubmed:author | pubmed-author:SakaiNN | lld:pubmed |
| pubmed-article:11322762 | pubmed:author | pubmed-author:KashiwagiHH | lld:pubmed |
| pubmed-article:11322762 | pubmed:author | pubmed-author:HiraokaHH | lld:pubmed |
| pubmed-article:11322762 | pubmed:author | pubmed-author:NozakiSS | lld:pubmed |
| pubmed-article:11322762 | pubmed:author | pubmed-author:TomiyamaYY | lld:pubmed |
| pubmed-article:11322762 | pubmed:author | pubmed-author:JanabiMM | lld:pubmed |
| pubmed-article:11322762 | pubmed:author | pubmed-author:Hirano KK | lld:pubmed |
| pubmed-article:11322762 | pubmed:copyrightInfo | Copyright 2001 Academic Press. | lld:pubmed |
| pubmed-article:11322762 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:11322762 | pubmed:day | 27 | lld:pubmed |
| pubmed-article:11322762 | pubmed:volume | 283 | lld:pubmed |
| pubmed-article:11322762 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:11322762 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:11322762 | pubmed:pagination | 26-30 | lld:pubmed |
| pubmed-article:11322762 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:11322762 | pubmed:meshHeading | pubmed-meshheading:11322762... | lld:pubmed |
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| pubmed-article:11322762 | pubmed:meshHeading | pubmed-meshheading:11322762... | lld:pubmed |
| pubmed-article:11322762 | pubmed:meshHeading | pubmed-meshheading:11322762... | lld:pubmed |
| pubmed-article:11322762 | pubmed:meshHeading | pubmed-meshheading:11322762... | lld:pubmed |
| pubmed-article:11322762 | pubmed:meshHeading | pubmed-meshheading:11322762... | lld:pubmed |
| pubmed-article:11322762 | pubmed:meshHeading | pubmed-meshheading:11322762... | lld:pubmed |
| pubmed-article:11322762 | pubmed:meshHeading | pubmed-meshheading:11322762... | lld:pubmed |
| pubmed-article:11322762 | pubmed:meshHeading | pubmed-meshheading:11322762... | lld:pubmed |
| pubmed-article:11322762 | pubmed:meshHeading | pubmed-meshheading:11322762... | lld:pubmed |
| pubmed-article:11322762 | pubmed:year | 2001 | lld:pubmed |
| pubmed-article:11322762 | pubmed:articleTitle | Reduced adhesion of monocyte-derived macrophages from CD36-deficient patients to type I collagen. | lld:pubmed |
| pubmed-article:11322762 | pubmed:affiliation | Department of Internal Medicine and Molecular Science, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan. | lld:pubmed |
| pubmed-article:11322762 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:11322762 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11322762 | lld:pubmed |
