| pubmed-article:11309348 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:11309348 | lifeskim:mentions | umls-concept:C0006142 | lld:lifeskim |
| pubmed-article:11309348 | lifeskim:mentions | umls-concept:C1512474 | lld:lifeskim |
| pubmed-article:11309348 | lifeskim:mentions | umls-concept:C0441655 | lld:lifeskim |
| pubmed-article:11309348 | lifeskim:mentions | umls-concept:C1515655 | lld:lifeskim |
| pubmed-article:11309348 | lifeskim:mentions | umls-concept:C0077063 | lld:lifeskim |
| pubmed-article:11309348 | pubmed:issue | 4 | lld:pubmed |
| pubmed-article:11309348 | pubmed:dateCreated | 2001-4-19 | lld:pubmed |
| pubmed-article:11309348 | pubmed:abstractText | Trichostatin A (TSA), an antifungal antibiotic with cytostatic and differentiating properties in mammalian cell culture, is a potent and specific inhibitor of histone deacetylase (HDAC) activity. The purpose of this study was to evaluate the antiproliferative and HDAC inhibitory activity of TSA in vitro in human breast cancer cell lines and to assess its antitumor efficacy and toxicity in vivo in a carcinogen-induced rat mammary cancer model. | lld:pubmed |
| pubmed-article:11309348 | pubmed:language | eng | lld:pubmed |
| pubmed-article:11309348 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11309348 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:11309348 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:11309348 | pubmed:month | Apr | lld:pubmed |
| pubmed-article:11309348 | pubmed:issn | 1078-0432 | lld:pubmed |
| pubmed-article:11309348 | pubmed:author | pubmed-author:ItoKK | lld:pubmed |
| pubmed-article:11309348 | pubmed:author | pubmed-author:CoombesR CRC | lld:pubmed |
| pubmed-article:11309348 | pubmed:author | pubmed-author:AliSS | lld:pubmed |
| pubmed-article:11309348 | pubmed:author | pubmed-author:PaceP EPE | lld:pubmed |
| pubmed-article:11309348 | pubmed:author | pubmed-author:VigushinD MDM | lld:pubmed |
| pubmed-article:11309348 | pubmed:author | pubmed-author:AdcockII | lld:pubmed |
| pubmed-article:11309348 | pubmed:author | pubmed-author:MirsaidiNN | lld:pubmed |
| pubmed-article:11309348 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:11309348 | pubmed:volume | 7 | lld:pubmed |
| pubmed-article:11309348 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:11309348 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:11309348 | pubmed:pagination | 971-6 | lld:pubmed |
| pubmed-article:11309348 | pubmed:dateRevised | 2009-11-19 | lld:pubmed |
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| pubmed-article:11309348 | pubmed:year | 2001 | lld:pubmed |
| pubmed-article:11309348 | pubmed:articleTitle | Trichostatin A is a histone deacetylase inhibitor with potent antitumor activity against breast cancer in vivo. | lld:pubmed |
| pubmed-article:11309348 | pubmed:affiliation | Department of Cancer Medicine, Cancer Research Campaign Laboratories, Imperial College of Science, Technology, and Medicine, Hammersmith Hospital, London, United Kingdom. d.vigushin@ic.ac.uk | lld:pubmed |
| pubmed-article:11309348 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:11309348 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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