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pubmed-article:11288212pubmed:abstractTextWe set out to determine whether chest radiographs obtained in premature infants between 9-16 days of age are predictive for the development of chronic lung disease of the newborn (CLD). This was a prospective cohort study. The study included 40 babies who were enrolled in a randomized trial of corticosteroid therapy for the prevention of CLD. Chest radiographs were obtained for clinical indications between 9-16 and 25-35 days of age. All chest radiographs were assessed by a single pediatric radiologist who was unaware of the treatment allocation and who used a previously published scoring system devised by Weinstein et al. [Pediatr Pulmonol 1994;18:284-289]. The radiographic score at 9-16 days correlated well with the radiographic score at 25-35 days of age (correlation coefficient, 0.69, P < or = 0.001). The scores at 9-16 days were significantly higher in those babies who had CLD at 28 days postnatal age (PNA) (P = 0.03) and at 36 weeks postmenstrual age (PMA) (P = 0.002). Using a receiver-operator characteristic curve, we have determined that for a radiographic score of 3 or greater at 9-16 days, the sensitivity for CLD was 0.64, and specificity was 0.84. We conclude that a chest radiograph taken between 9-16 days may help predict which at-risk preterm infants will develop CLD.lld:pubmed
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pubmed-article:11288212pubmed:authorpubmed-author:TeeleR LRLlld:pubmed
pubmed-article:11288212pubmed:authorpubmed-author:HardingJ EJElld:pubmed
pubmed-article:11288212pubmed:authorpubmed-author:ClarkP WPWlld:pubmed
pubmed-article:11288212pubmed:authorpubmed-author:BloomfieldF...lld:pubmed
pubmed-article:11288212pubmed:copyrightInfoCopyright 2001 Wiley-Liss, Inc.lld:pubmed
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pubmed-article:11288212pubmed:volume31lld:pubmed
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pubmed-article:11288212pubmed:pagination297-300lld:pubmed
pubmed-article:11288212pubmed:dateRevised2006-3-28lld:pubmed
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pubmed-article:11288212pubmed:year2001lld:pubmed
pubmed-article:11288212pubmed:articleTitleEarly chest radiographs in very low birth weight babies receiving corticosteroids for lung disease.lld:pubmed
pubmed-article:11288212pubmed:affiliationDepartments of Paediatrics and Radiology, National Women's Hospital, Auckland, New Zealand.lld:pubmed
pubmed-article:11288212pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:11288212pubmed:publicationTypeClinical Triallld:pubmed
pubmed-article:11288212pubmed:publicationTypeRandomized Controlled Triallld:pubmed
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