| pubmed-article:11197157 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:11197157 | lifeskim:mentions | umls-concept:C0220825 | lld:lifeskim |
| pubmed-article:11197157 | lifeskim:mentions | umls-concept:C0596973 | lld:lifeskim |
| pubmed-article:11197157 | lifeskim:mentions | umls-concept:C1704970 | lld:lifeskim |
| pubmed-article:11197157 | lifeskim:mentions | umls-concept:C0201699 | lld:lifeskim |
| pubmed-article:11197157 | lifeskim:mentions | umls-concept:C0599219 | lld:lifeskim |
| pubmed-article:11197157 | pubmed:issue | 1 | lld:pubmed |
| pubmed-article:11197157 | pubmed:dateCreated | 2001-1-25 | lld:pubmed |
| pubmed-article:11197157 | pubmed:abstractText | Norbornen-5-yl carboxylic acid and norbornen-5-ylmethylsilyl ether-based beta-cyclodextrins (beta-CDs) containing up to three norbornene ester and up to five norbornene silyl ether units have been prepared from beta-CD and norbornen-5-carboxylic chloride and norbornen-5-ylmethyldichlorosilane, respectively. Oligomers (n = 2-4) were prepared therefrom using ring-opening metathesis polymerization (ROMP). Monomeric and oligomeric substituted beta-CDs were evaluated as chiral selectors in nonaqueous capillary zone electrophoresis using 35 mM sodium bicarbonate in N-methylformamide (NMF) as background electrolyte. Both monomeric and oligomeric norbornene ester- and norbornene silyl ether-type selectors showed good enantioresolution for dansylated (DNS-) amino acids using concentrations of the chiral selector of up to 4% w/v. A significant improvement in resolution was observed upon the introduction of up to five norbornene silyl ether units into a beta-CD molecule, whereas higher degrees of substitution with norbornen-5-yl-carboxyl groups lead to a reduction in enantioresolution of DNS-amino acids. Thus, pentakis(norbornen-5-ylmethylhydroxysiloxyl)-beta-CD turned out to be superior to mono(norbornen-5-ylmethylhydroxysiloxyl)-beta-CD in terms of enantioresolution. Moreover, norbornene silyl ether-type selectors were found to be more efficient than norbornene ester-type selectors. Finally, oligomeric selectors were found to possess superior or at least comparable enantioselectivity in the separation of DNS-amino acids compared to the parent monomers. A maximum in enantioresolution was obtained with oligo(pentakis(norbornen-5-ylmethylhydroxysiloxyl)beta-CD). | lld:pubmed |
| pubmed-article:11197157 | pubmed:language | eng | lld:pubmed |
| pubmed-article:11197157 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11197157 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:11197157 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11197157 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11197157 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11197157 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11197157 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11197157 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11197157 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:11197157 | pubmed:month | Jan | lld:pubmed |
| pubmed-article:11197157 | pubmed:issn | 0173-0835 | lld:pubmed |
| pubmed-article:11197157 | pubmed:author | pubmed-author:EdelAA | lld:pubmed |
| pubmed-article:11197157 | pubmed:author | pubmed-author:HuberC GCG | lld:pubmed |
| pubmed-article:11197157 | pubmed:author | pubmed-author:BuchmeiserM... | lld:pubmed |
| pubmed-article:11197157 | pubmed:author | pubmed-author:SinnerFF | lld:pubmed |
| pubmed-article:11197157 | pubmed:author | pubmed-author:MupaMM | lld:pubmed |
| pubmed-article:11197157 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:11197157 | pubmed:volume | 22 | lld:pubmed |
| pubmed-article:11197157 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:11197157 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:11197157 | pubmed:pagination | 109-16 | lld:pubmed |
| pubmed-article:11197157 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:11197157 | pubmed:meshHeading | pubmed-meshheading:11197157... | lld:pubmed |
| pubmed-article:11197157 | pubmed:meshHeading | pubmed-meshheading:11197157... | lld:pubmed |
| pubmed-article:11197157 | pubmed:meshHeading | pubmed-meshheading:11197157... | lld:pubmed |
| pubmed-article:11197157 | pubmed:meshHeading | pubmed-meshheading:11197157... | lld:pubmed |
| pubmed-article:11197157 | pubmed:meshHeading | pubmed-meshheading:11197157... | lld:pubmed |
| pubmed-article:11197157 | pubmed:meshHeading | pubmed-meshheading:11197157... | lld:pubmed |
| pubmed-article:11197157 | pubmed:meshHeading | pubmed-meshheading:11197157... | lld:pubmed |
| pubmed-article:11197157 | pubmed:meshHeading | pubmed-meshheading:11197157... | lld:pubmed |
| pubmed-article:11197157 | pubmed:year | 2001 | lld:pubmed |
| pubmed-article:11197157 | pubmed:articleTitle | Evaluation of norbornene- beta-cyclodextrin-based monomers and oligomers as chiral selectors by means of nonaqueous capillary electrophoresis. | lld:pubmed |
| pubmed-article:11197157 | pubmed:affiliation | Institute of Analytical Chemistry and Radiochemistry, Leopold-Franzens-University, Innsbruck, Austria. | lld:pubmed |
| pubmed-article:11197157 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:11197157 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
