pubmed-article:11152441 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:11152441 | lifeskim:mentions | umls-concept:C0030705 | lld:lifeskim |
pubmed-article:11152441 | lifeskim:mentions | umls-concept:C0039194 | lld:lifeskim |
pubmed-article:11152441 | lifeskim:mentions | umls-concept:C0162638 | lld:lifeskim |
pubmed-article:11152441 | lifeskim:mentions | umls-concept:C0376705 | lld:lifeskim |
pubmed-article:11152441 | lifeskim:mentions | umls-concept:C0441889 | lld:lifeskim |
pubmed-article:11152441 | lifeskim:mentions | umls-concept:C0332281 | lld:lifeskim |
pubmed-article:11152441 | lifeskim:mentions | umls-concept:C1332714 | lld:lifeskim |
pubmed-article:11152441 | lifeskim:mentions | umls-concept:C0205322 | lld:lifeskim |
pubmed-article:11152441 | lifeskim:mentions | umls-concept:C0887947 | lld:lifeskim |
pubmed-article:11152441 | pubmed:issue | 1 | lld:pubmed |
pubmed-article:11152441 | pubmed:dateCreated | 2001-1-26 | lld:pubmed |
pubmed-article:11152441 | pubmed:abstractText | Apoptosis is one of the mechanisms involved in the persistent CD4(+) T cell lymphopenia occurring in human immunodeficiency virus (HIV)-infected patients treated with highly active antiretroviral therapy (HAART). The aim of this study was to look at the relationship between the level of T cell apoptosis in patients on HAART and their HIV viral load measurement. Forty-five patients receiving HAART for a median time of 5 months were included: 13 had an undetectable viral load and 32 had a viral load > or = 200 copies/mL. No relationship was observed between the level of spontaneous T cell apoptosis and the viral load measurement. Patients with a viral load > or = 200 copies/mL exhibited a significantly higher level of CD4-induced apoptosis of CD4(+) T cells, compared with patients with undetectable viraemia (38 versus 15%, respectively, P = 0.03). Activation-induced apoptosis may be involved in the paucity of the immune reconstitution observed in HIV-infected patients treated with HAART. | lld:pubmed |
pubmed-article:11152441 | pubmed:language | eng | lld:pubmed |
pubmed-article:11152441 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:11152441 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:11152441 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:11152441 | pubmed:month | Jan | lld:pubmed |
pubmed-article:11152441 | pubmed:issn | 0305-7453 | lld:pubmed |
pubmed-article:11152441 | pubmed:author | pubmed-author:BernardAA | lld:pubmed |
pubmed-article:11152441 | pubmed:author | pubmed-author:DellamonicaPP | lld:pubmed |
pubmed-article:11152441 | pubmed:author | pubmed-author:BreittmayerJ... | lld:pubmed |
pubmed-article:11152441 | pubmed:author | pubmed-author:CottalordaJJ | lld:pubmed |
pubmed-article:11152441 | pubmed:author | pubmed-author:MondainVV | lld:pubmed |
pubmed-article:11152441 | pubmed:author | pubmed-author:TicchioniMM | lld:pubmed |
pubmed-article:11152441 | pubmed:author | pubmed-author:RogerP MPM | lld:pubmed |
pubmed-article:11152441 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:11152441 | pubmed:volume | 47 | lld:pubmed |
pubmed-article:11152441 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:11152441 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:11152441 | pubmed:pagination | 109-12 | lld:pubmed |
pubmed-article:11152441 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
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pubmed-article:11152441 | pubmed:year | 2001 | lld:pubmed |
pubmed-article:11152441 | pubmed:articleTitle | Persistent viral load in patients on HAART is associated with a higher level of activation-induced apoptosis of CD4(+) T cells. | lld:pubmed |
pubmed-article:11152441 | pubmed:affiliation | Service des Maladies Infectieuses et Tropicales, Hôpital de l'Archet, Nice, France. | lld:pubmed |
pubmed-article:11152441 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:11152441 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |