| pubmed-article:11123362 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:11123362 | lifeskim:mentions | umls-concept:C0175677 | lld:lifeskim |
| pubmed-article:11123362 | lifeskim:mentions | umls-concept:C0026809 | lld:lifeskim |
| pubmed-article:11123362 | lifeskim:mentions | umls-concept:C0033684 | lld:lifeskim |
| pubmed-article:11123362 | lifeskim:mentions | umls-concept:C0030956 | lld:lifeskim |
| pubmed-article:11123362 | lifeskim:mentions | umls-concept:C0085094 | lld:lifeskim |
| pubmed-article:11123362 | lifeskim:mentions | umls-concept:C1704632 | lld:lifeskim |
| pubmed-article:11123362 | lifeskim:mentions | umls-concept:C0871261 | lld:lifeskim |
| pubmed-article:11123362 | lifeskim:mentions | umls-concept:C1423715 | lld:lifeskim |
| pubmed-article:11123362 | lifeskim:mentions | umls-concept:C2911692 | lld:lifeskim |
| pubmed-article:11123362 | lifeskim:mentions | umls-concept:C1706817 | lld:lifeskim |
| pubmed-article:11123362 | lifeskim:mentions | umls-concept:C1441547 | lld:lifeskim |
| pubmed-article:11123362 | pubmed:issue | 1 | lld:pubmed |
| pubmed-article:11123362 | pubmed:dateCreated | 2001-2-2 | lld:pubmed |
| pubmed-article:11123362 | pubmed:abstractText | Brain injury induces disruption of the blood-brain barrier, edema, and release of autodestructive factors that produce delayed neuronal damage. NAPSVIPQ (NAP), a femtomolar-acting peptide, is shown to be neuroprotective in a mouse model of closed head injury. NAP injection after injury reduced mortality and facilitated neurobehavioral recovery (P < 0.005). Edema was reduced by 70% in the NAP-treated mice (P < 0.01). Furthermore, in vivo magnetic resonance imaging demonstrated significant brain-tissue recovery in the NAP-treated animals. NAP treatment decreased tumor necrosis factor-alpha levels in the injured brain and was shown to protect pheochromocytoma (PC12 cells) against tumor necrosis factor-alpha-induced toxicity. Thus, NAP provides significant amelioration from the complex array of injuries elicited by head trauma. | lld:pubmed |
| pubmed-article:11123362 | pubmed:language | eng | lld:pubmed |
| pubmed-article:11123362 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11123362 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:11123362 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11123362 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:11123362 | pubmed:month | Jan | lld:pubmed |
| pubmed-article:11123362 | pubmed:issn | 0022-3565 | lld:pubmed |
| pubmed-article:11123362 | pubmed:author | pubmed-author:AssafYY | lld:pubmed |
| pubmed-article:11123362 | pubmed:author | pubmed-author:BrennemanD... | lld:pubmed |
| pubmed-article:11123362 | pubmed:author | pubmed-author:ShohamiEE | lld:pubmed |
| pubmed-article:11123362 | pubmed:author | pubmed-author:CohenYY | lld:pubmed |
| pubmed-article:11123362 | pubmed:author | pubmed-author:GozesII | lld:pubmed |
| pubmed-article:11123362 | pubmed:author | pubmed-author:EizenbergOO | lld:pubmed |
| pubmed-article:11123362 | pubmed:author | pubmed-author:SteingartR... | lld:pubmed |
| pubmed-article:11123362 | pubmed:author | pubmed-author:Beni-AdaniLL | lld:pubmed |
| pubmed-article:11123362 | pubmed:author | pubmed-author:TrembolverVV | lld:pubmed |
| pubmed-article:11123362 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:11123362 | pubmed:volume | 296 | lld:pubmed |
| pubmed-article:11123362 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:11123362 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:11123362 | pubmed:pagination | 57-63 | lld:pubmed |
| pubmed-article:11123362 | pubmed:dateRevised | 2011-7-13 | lld:pubmed |
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| pubmed-article:11123362 | pubmed:year | 2001 | lld:pubmed |
| pubmed-article:11123362 | pubmed:articleTitle | A peptide derived from activity-dependent neuroprotective protein (ADNP) ameliorates injury response in closed head injury in mice. | lld:pubmed |
| pubmed-article:11123362 | pubmed:affiliation | Department of Neurosurgery, The Hebrew University Hadassah Medical Center, Jerusalem, Israel. | lld:pubmed |
| pubmed-article:11123362 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:11123362 | pubmed:publicationType | Research Support, U.S. Gov't, Non-P.H.S. | lld:pubmed |
| pubmed-article:11123362 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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