| pubmed-article:11122517 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:11122517 | lifeskim:mentions | umls-concept:C0085356 | lld:lifeskim |
| pubmed-article:11122517 | lifeskim:mentions | umls-concept:C0026336 | lld:lifeskim |
| pubmed-article:11122517 | lifeskim:mentions | umls-concept:C0040952 | lld:lifeskim |
| pubmed-article:11122517 | lifeskim:mentions | umls-concept:C1707391 | lld:lifeskim |
| pubmed-article:11122517 | pubmed:issue | 6 | lld:pubmed |
| pubmed-article:11122517 | pubmed:dateCreated | 2002-5-6 | lld:pubmed |
| pubmed-article:11122517 | pubmed:abstractText | Trichothecenes are potent inhibitors of cytoplasmic protein synthesis which can affect the severity of plant diseases such as wheat head scab. While many trichothecene-producing fungi share the initial biosynthetic intermediates, Fusarium sp. are unique in the production of trichothecenes containing an oxygen function at C-3. Although the initial trichothecene and the final products have a C-3 hydroxyl group, the intermediate steps are acetylated at C-3. By using Chlamydomonas reinhardtii, a unicellular plant with a well-defined genetic system, we were able to test the proposal that trichothecenes with a C-3 hydroxyl are more toxic to plants, as well as demonstrate that C. reinhardtii is a promising plant trichothecene bioassay system. Seven pairs of trichothecenes with either a C-3 hydroxyl or C-3 acetyl group were assayed. Our results confirm that trichothecenes acetylated at C-3 were far less toxic to Chlamydomonas than those with a C-3 hydroxyl group. | lld:pubmed |
| pubmed-article:11122517 | pubmed:language | eng | lld:pubmed |
| pubmed-article:11122517 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11122517 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:11122517 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11122517 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:11122517 | pubmed:issn | 1056-9014 | lld:pubmed |
| pubmed-article:11122517 | pubmed:author | pubmed-author:AlexanderN... | lld:pubmed |
| pubmed-article:11122517 | pubmed:author | pubmed-author:McCormickS... | lld:pubmed |
| pubmed-article:11122517 | pubmed:author | pubmed-author:ZiegenhornS... | lld:pubmed |
| pubmed-article:11122517 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:11122517 | pubmed:volume | 7 | lld:pubmed |
| pubmed-article:11122517 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:11122517 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:11122517 | pubmed:pagination | 265-9 | lld:pubmed |
| pubmed-article:11122517 | pubmed:dateRevised | 2003-11-14 | lld:pubmed |
| pubmed-article:11122517 | pubmed:meshHeading | pubmed-meshheading:11122517... | lld:pubmed |
| pubmed-article:11122517 | pubmed:meshHeading | pubmed-meshheading:11122517... | lld:pubmed |
| pubmed-article:11122517 | pubmed:meshHeading | pubmed-meshheading:11122517... | lld:pubmed |
| pubmed-article:11122517 | pubmed:meshHeading | pubmed-meshheading:11122517... | lld:pubmed |
| pubmed-article:11122517 | pubmed:meshHeading | pubmed-meshheading:11122517... | lld:pubmed |
| pubmed-article:11122517 | pubmed:meshHeading | pubmed-meshheading:11122517... | lld:pubmed |
| pubmed-article:11122517 | pubmed:year | 1999 | lld:pubmed |
| pubmed-article:11122517 | pubmed:articleTitle | Phytotoxicity of selected trichothecenes using Chlamydomonas reinhardtii as a model systemt. | lld:pubmed |
| pubmed-article:11122517 | pubmed:affiliation | Mycotoxin Research Unit, USDA/ARS, National Center for Agricutural Utilization Research, Peoria, Illinois 61604, USA. alexannj@mail.ncaur.usda.gov | lld:pubmed |
| pubmed-article:11122517 | pubmed:publicationType | Journal Article | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11122517 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11122517 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11122517 | lld:pubmed |
