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pubmed-article:11115078pubmed:abstractTextGlomerular distention is associated with cellular mechanical strain. In addition, glomerular distention/contraction is assumed to influence the filtration rate through changes in filtration surface area. A contractile cytoskeleton in podocytes and mesangial cells, formed by F-actin-containing stress fibers, maintains structural integrity and modulates glomerular expansion. In this study, the glomerular cell distribution of F-actin and vimentin filaments was studied in normal control and nine-month streptozotocin-diabetic rats. Results in situ were compared with observations in tissue culture.lld:pubmed
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pubmed-article:11115078pubmed:articleTitleF-actin fiber distribution in glomerular cells: structural and functional implications.lld:pubmed
pubmed-article:11115078pubmed:affiliationDivision of Nephrology and Hypertension, Department of Medicine, Henry Ford Hospital, Detroit, Michigan 48202, USA. cortes.pedro@usa.netlld:pubmed
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