| pubmed-article:11050251 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:11050251 | lifeskim:mentions | umls-concept:C0027882 | lld:lifeskim |
| pubmed-article:11050251 | lifeskim:mentions | umls-concept:C0015127 | lld:lifeskim |
| pubmed-article:11050251 | lifeskim:mentions | umls-concept:C0521390 | lld:lifeskim |
| pubmed-article:11050251 | lifeskim:mentions | umls-concept:C0035253 | lld:lifeskim |
| pubmed-article:11050251 | lifeskim:mentions | umls-concept:C1314792 | lld:lifeskim |
| pubmed-article:11050251 | lifeskim:mentions | umls-concept:C0017262 | lld:lifeskim |
| pubmed-article:11050251 | lifeskim:mentions | umls-concept:C0295893 | lld:lifeskim |
| pubmed-article:11050251 | lifeskim:mentions | umls-concept:C1419346 | lld:lifeskim |
| pubmed-article:11050251 | lifeskim:mentions | umls-concept:C1154402 | lld:lifeskim |
| pubmed-article:11050251 | lifeskim:mentions | umls-concept:C0743559 | lld:lifeskim |
| pubmed-article:11050251 | lifeskim:mentions | umls-concept:C1515655 | lld:lifeskim |
| pubmed-article:11050251 | lifeskim:mentions | umls-concept:C2911684 | lld:lifeskim |
| pubmed-article:11050251 | lifeskim:mentions | umls-concept:C0185117 | lld:lifeskim |
| pubmed-article:11050251 | pubmed:issue | 22 | lld:pubmed |
| pubmed-article:11050251 | pubmed:dateCreated | 2000-11-28 | lld:pubmed |
| pubmed-article:11050251 | pubmed:abstractText | The neuron-restrictive silencer factor (NRSF; also known as REST for repressor element-1 silencing transcription factor) is a transcriptional repressor of multiple neuronal genes, but little is known about its function in vivo. NRSF is normally down-regulated upon neuronal differentiation. Constitutive expression of NRSF in the developing spinal cord of chicken embryos caused repression of two endogenous target genes, N-tubulin and Ng-CAM, but did not prevent overt neurogenesis. Nevertheless, commissural neurons that differentiated while constitutively expressing NRSF showed a significantly increased frequency of axon guidance errors. These data suggest that down-regulation of NRSF is necessary for the proper development of at least some classes of neurons in vivo. | lld:pubmed |
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| pubmed-article:11050251 | pubmed:language | eng | lld:pubmed |
| pubmed-article:11050251 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11050251 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:11050251 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
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| pubmed-article:11050251 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:11050251 | pubmed:month | Oct | lld:pubmed |
| pubmed-article:11050251 | pubmed:issn | 0027-8424 | lld:pubmed |
| pubmed-article:11050251 | pubmed:author | pubmed-author:AndersonD JDJ | lld:pubmed |
| pubmed-article:11050251 | pubmed:author | pubmed-author:PerezS ESE | lld:pubmed |
| pubmed-article:11050251 | pubmed:author | pubmed-author:PaquetteA JAJ | lld:pubmed |
| pubmed-article:11050251 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:11050251 | pubmed:day | 24 | lld:pubmed |
| pubmed-article:11050251 | pubmed:volume | 97 | lld:pubmed |
| pubmed-article:11050251 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:11050251 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:11050251 | pubmed:pagination | 12318-23 | lld:pubmed |
| pubmed-article:11050251 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
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