| pubmed-article:11027976 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:11027976 | lifeskim:mentions | umls-concept:C0032098 | lld:lifeskim |
| pubmed-article:11027976 | lifeskim:mentions | umls-concept:C2349001 | lld:lifeskim |
| pubmed-article:11027976 | lifeskim:mentions | umls-concept:C0178856 | lld:lifeskim |
| pubmed-article:11027976 | lifeskim:mentions | umls-concept:C0681850 | lld:lifeskim |
| pubmed-article:11027976 | lifeskim:mentions | umls-concept:C1706203 | lld:lifeskim |
| pubmed-article:11027976 | lifeskim:mentions | umls-concept:C2697811 | lld:lifeskim |
| pubmed-article:11027976 | lifeskim:mentions | umls-concept:C0024264 | lld:lifeskim |
| pubmed-article:11027976 | lifeskim:mentions | umls-concept:C0026004 | lld:lifeskim |
| pubmed-article:11027976 | lifeskim:mentions | umls-concept:C1707455 | lld:lifeskim |
| pubmed-article:11027976 | lifeskim:mentions | umls-concept:C1550501 | lld:lifeskim |
| pubmed-article:11027976 | lifeskim:mentions | umls-concept:C0439603 | lld:lifeskim |
| pubmed-article:11027976 | pubmed:issue | 2 | lld:pubmed |
| pubmed-article:11027976 | pubmed:dateCreated | 2000-11-27 | lld:pubmed |
| pubmed-article:11027976 | pubmed:abstractText | Spontaneous baseline frequencies of micronuclei in mono-, bi- and poly-nucleated lymphocytes were analyzed, using the cytokinesis-block technique, in 103 subjects living in a residential suburb (Genova-Nervi), and in 203 subjects living in an urban industrialized area near a metallurgical plant and a coke factory (Genova-Cornigliano). Statistical analysis showed that the average frequency of micronucleated binucleated lymphocytes (MnBNL) was significantly higher (1.42-fold) in donors of Nervi than in donors of Cornigliano living in a contaminated environment. In contrast, the average frequency of micronucleated polynucleated lymphocytes (MnPNL) was significantly higher (1.66-fold) in donors of Cornigliano than in donors of Nervi. The existence in the whole population examined of a positive correlation between frequency of MnBNL and frequency of MnPNL and the absence of a positive correlation between frequency of bi- and poly-nucleated lymphocytes and frequency of MnPNL suggest that the formation of MnPNL is a consequence of genetic damage and not of mitotic errors arising during the division of bi- and poly-nucleated cells. In agreement with previous findings the frequency of MnBNL increased with age and was significantly higher in females than in males; unexpectedly it was higher in non-smokers/non-drinkers than in smokers/drinkers. | lld:pubmed |
| pubmed-article:11027976 | pubmed:language | eng | lld:pubmed |
| pubmed-article:11027976 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11027976 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:11027976 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:11027976 | pubmed:month | Oct | lld:pubmed |
| pubmed-article:11027976 | pubmed:issn | 0027-5107 | lld:pubmed |
| pubmed-article:11027976 | pubmed:author | pubmed-author:BrambillaGG | lld:pubmed |
| pubmed-article:11027976 | pubmed:author | pubmed-author:GiulianiRR | lld:pubmed |
| pubmed-article:11027976 | pubmed:author | pubmed-author:CossuGG | lld:pubmed |
| pubmed-article:11027976 | pubmed:author | pubmed-author:MartelliAA | lld:pubmed |
| pubmed-article:11027976 | pubmed:author | pubmed-author:RobbianoLL | lld:pubmed |
| pubmed-article:11027976 | pubmed:author | pubmed-author:PerroniGG | lld:pubmed |
| pubmed-article:11027976 | pubmed:author | pubmed-author:TagliazucchiA... | lld:pubmed |
| pubmed-article:11027976 | pubmed:author | pubmed-author:ArescaG FGF | lld:pubmed |
| pubmed-article:11027976 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:11027976 | pubmed:day | 31 | lld:pubmed |
| pubmed-article:11027976 | pubmed:volume | 470 | lld:pubmed |
| pubmed-article:11027976 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:11027976 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:11027976 | pubmed:pagination | 211-9 | lld:pubmed |
| pubmed-article:11027976 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:11027976 | pubmed:meshHeading | pubmed-meshheading:11027976... | lld:pubmed |
| pubmed-article:11027976 | pubmed:meshHeading | pubmed-meshheading:11027976... | lld:pubmed |
| pubmed-article:11027976 | pubmed:meshHeading | pubmed-meshheading:11027976... | lld:pubmed |
| pubmed-article:11027976 | pubmed:meshHeading | pubmed-meshheading:11027976... | lld:pubmed |
| pubmed-article:11027976 | pubmed:meshHeading | pubmed-meshheading:11027976... | lld:pubmed |
| pubmed-article:11027976 | pubmed:meshHeading | pubmed-meshheading:11027976... | lld:pubmed |
| pubmed-article:11027976 | pubmed:meshHeading | pubmed-meshheading:11027976... | lld:pubmed |
| pubmed-article:11027976 | pubmed:year | 2000 | lld:pubmed |
| pubmed-article:11027976 | pubmed:articleTitle | Comparison of micronuclei frequencies in mono-, bi- and poly-nucleated lymphocytes from subjects of a residential suburb and subjects living near a metallurgical plant. | lld:pubmed |
| pubmed-article:11027976 | pubmed:affiliation | Department of Internal Medicine, Division of Clinical Pharmacology and Toxicology, University of Genoa, Viale Benedetto XV 2, I-16132, Genoa, Italy. | lld:pubmed |
| pubmed-article:11027976 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:11027976 | pubmed:publicationType | Comparative Study | lld:pubmed |
| pubmed-article:11027976 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
