| pubmed-article:10982176 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:10982176 | lifeskim:mentions | umls-concept:C0011854 | lld:lifeskim |
| pubmed-article:10982176 | lifeskim:mentions | umls-concept:C0796366 | lld:lifeskim |
| pubmed-article:10982176 | lifeskim:mentions | umls-concept:C1708726 | lld:lifeskim |
| pubmed-article:10982176 | lifeskim:mentions | umls-concept:C1415869 | lld:lifeskim |
| pubmed-article:10982176 | lifeskim:mentions | umls-concept:C1838261 | lld:lifeskim |
| pubmed-article:10982176 | lifeskim:mentions | umls-concept:C1333530 | lld:lifeskim |
| pubmed-article:10982176 | lifeskim:mentions | umls-concept:C1414945 | lld:lifeskim |
| pubmed-article:10982176 | lifeskim:mentions | umls-concept:C0220825 | lld:lifeskim |
| pubmed-article:10982176 | lifeskim:mentions | umls-concept:C0936012 | lld:lifeskim |
| pubmed-article:10982176 | lifeskim:mentions | umls-concept:C0392760 | lld:lifeskim |
| pubmed-article:10982176 | lifeskim:mentions | umls-concept:C1332838 | lld:lifeskim |
| pubmed-article:10982176 | pubmed:issue | 1 | lld:pubmed |
| pubmed-article:10982176 | pubmed:dateCreated | 2000-9-22 | lld:pubmed |
| pubmed-article:10982176 | pubmed:abstractText | Previous studies have identified a susceptibility region for insulin-dependent (type 1) diabetes mellitus on chromosome 11q13 (IDDM4). In this study, 15 polymorphic markers were analyzed for 382 affected sibpair (ASP) families with type 1 diabetes. Our analyses provided additional evidence for linkage for IDDM4 (a peak LOD score of 3.4 at D11S913). The markers with strong linkage evidence are located within an interval of approximately 6 cM between D11S4205 and GALN. We also identified polymorphisms in two candidate genes, Fas-associated death domain protein (FADD) and galanin (GALN). Analyses of the data by transmission/disequilibrium test (TDT) and extended TDT (ETDT) did not provide any evidence for association/linkage with these candidate genes. However, ETDT did reveal significant association/linkage with the marker D11S987 (P=0.0004) within the IDDM4 interval defined by ASP analyses, suggesting that IDDM4 may be in the close proximity of D11S987. | lld:pubmed |
| pubmed-article:10982176 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10982176 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10982176 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10982176 | pubmed:language | eng | lld:pubmed |
| pubmed-article:10982176 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10982176 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:10982176 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10982176 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10982176 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10982176 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10982176 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10982176 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10982176 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:10982176 | pubmed:month | Jan | lld:pubmed |
| pubmed-article:10982176 | pubmed:issn | 0340-6717 | lld:pubmed |
| pubmed-article:10982176 | pubmed:author | pubmed-author:YangM CMC | lld:pubmed |
| pubmed-article:10982176 | pubmed:author | pubmed-author:YangJ JJJ | lld:pubmed |
| pubmed-article:10982176 | pubmed:author | pubmed-author:NichollsRR | lld:pubmed |
| pubmed-article:10982176 | pubmed:author | pubmed-author:SheJ XJX | lld:pubmed |
| pubmed-article:10982176 | pubmed:author | pubmed-author:MarronM PMP | lld:pubmed |
| pubmed-article:10982176 | pubmed:author | pubmed-author:EckenrodeSS | lld:pubmed |
| pubmed-article:10982176 | pubmed:author | pubmed-author:Guida... | lld:pubmed |
| pubmed-article:10982176 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:10982176 | pubmed:volume | 106 | lld:pubmed |
| pubmed-article:10982176 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:10982176 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:10982176 | pubmed:pagination | 14-8 | lld:pubmed |
| pubmed-article:10982176 | pubmed:dateRevised | 2007-11-14 | lld:pubmed |
| pubmed-article:10982176 | pubmed:meshHeading | pubmed-meshheading:10982176... | lld:pubmed |
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| pubmed-article:10982176 | pubmed:meshHeading | pubmed-meshheading:10982176... | lld:pubmed |
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| pubmed-article:10982176 | pubmed:meshHeading | pubmed-meshheading:10982176... | lld:pubmed |
| pubmed-article:10982176 | pubmed:meshHeading | pubmed-meshheading:10982176... | lld:pubmed |
| pubmed-article:10982176 | pubmed:meshHeading | pubmed-meshheading:10982176... | lld:pubmed |
| pubmed-article:10982176 | pubmed:meshHeading | pubmed-meshheading:10982176... | lld:pubmed |
| pubmed-article:10982176 | pubmed:meshHeading | pubmed-meshheading:10982176... | lld:pubmed |
| pubmed-article:10982176 | pubmed:meshHeading | pubmed-meshheading:10982176... | lld:pubmed |
| pubmed-article:10982176 | pubmed:meshHeading | pubmed-meshheading:10982176... | lld:pubmed |
| pubmed-article:10982176 | pubmed:meshHeading | pubmed-meshheading:10982176... | lld:pubmed |
| pubmed-article:10982176 | pubmed:meshHeading | pubmed-meshheading:10982176... | lld:pubmed |
| pubmed-article:10982176 | pubmed:meshHeading | pubmed-meshheading:10982176... | lld:pubmed |
| pubmed-article:10982176 | pubmed:meshHeading | pubmed-meshheading:10982176... | lld:pubmed |
| pubmed-article:10982176 | pubmed:meshHeading | pubmed-meshheading:10982176... | lld:pubmed |
| pubmed-article:10982176 | pubmed:year | 2000 | lld:pubmed |
| pubmed-article:10982176 | pubmed:articleTitle | Fine-mapping of the type 1 diabetes locus (IDDM4) on chromosome 11q and evaluation of two candidate genes (FADD and GALN) by affected sibpair and linkage-disequilibrium analyses. | lld:pubmed |
| pubmed-article:10982176 | pubmed:affiliation | Department of Pathology, Immunology and Laboratory Medicine, and Center for Mammalian Genetics, College of Medicine, University of Florida, Gainesville 32610, USA. | lld:pubmed |
| pubmed-article:10982176 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:10982176 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:10982176 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10982176 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10982176 | lld:pubmed |
