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pubmed-article:10919571pubmed:abstractTextA rat pancreas transplantation model with insulin-dependent diabetes mellitus (IDDM) recurrence was established using a Wistar-Furth (WF; RT1u, RT6.2) rat as a donor and diabetes-prone (DP; RT1u, rt6.1 gene carrier) BioBreeding rat as a recipient. Interestingly, NKR-P1+TCRalphabeta+ (NKT) cells have recently been reported to have immunoregulatory functions in preventing autoimmune diabetes. The purpose of this study was to specifically examine the contribution of NKT cells in the prevention of IDDM recurrence.lld:pubmed
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pubmed-article:10919571pubmed:articleTitleImportance of donor-derived lymphocytes in the protection of pancreaticoduodenal or islet grafts from recurrent autoimmunity: a role for RT6+NKR-P1+ T cells.lld:pubmed
pubmed-article:10919571pubmed:affiliationDepartment of Bioregulation, Biomedical Research Center, Osaka University Graduate School of Medicine, Japan.lld:pubmed
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