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pubmed-article:10905591pubmed:abstractTextWe have previously reported a recombinant vaccinia-based vaccine (vac-Sig/E7/LAMP-1) that demonstrated a significant anti-tumor effect in a subcutaneous tumor challenge model. Since the liver is one of the most common sites for tumor metastasis and organ microenvironments may modulate tumor cell responses to therapies, the aim of the present study was to evaluate the potency of vac-Sig/E7/LAMP-1 in treating E7-expressing tumors grown in the liver.lld:pubmed
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pubmed-article:10905591pubmed:articleTitleAntigen-specific immunotherapy for human papillomavirus 16 E7-expressing tumors grown in the liver.lld:pubmed
pubmed-article:10905591pubmed:affiliationDepartment of Oncology, The Johns Hopkins Medical Institutions, Baltimore, Maryland, USA.lld:pubmed
pubmed-article:10905591pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:10905591pubmed:publicationTypeResearch Support, U.S. Gov't, P.H.S.lld:pubmed
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