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pubmed-article:10853668pubmed:abstractTextA series of indole and carbazole based inhibitors of factor Xa (FXa) has been investigated. The most potent compound inhibits FXa with a Ki of 0.2 nM and has 900- and 750-fold selectivity over thrombin and trypsin, respectively.lld:pubmed
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pubmed-article:10853668pubmed:articleTitleDesign, synthesis, and in vitro biological activity of indole-based factor Xa inhibitors.lld:pubmed
pubmed-article:10853668pubmed:affiliationDiscovery Research, Berlex Biosciences, Richmond, CA 94804, USA. damian_arnaiz@berlex.comlld:pubmed
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