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pubmed-article:1083513pubmed:dateCreated1976-7-6lld:pubmed
pubmed-article:1083513pubmed:abstractTextPeripheral blood lymphocytes were investigated in 20 patients with acute viral hepatitis. For assessment of B lymphocytes the rosette test was carried out using sheep erythrocytes coated with antibodies and murine complement. T lymphocytes were recognized by their ability of binding uncoated sheep erythrocytes. In 16 cases the results of EAC test in patients with viral hepatitis resembled those in healthy donors. In 3 cases a significant decrease was observed and in one case a significant rise was found in the number of cells forming EAC rosettes. The T lymphocyte count was within normal range in 19 investigated cases. The results suggest that impaired T lymphocyte reactivity to PHA in acute viral hepatitis is due to a disturbed function of T lymphocytes and not to a decrease in their number. In cases associated with significant hepatocellular damage a reduction in the number of circulating B lymphocytes was observed.lld:pubmed
pubmed-article:1083513pubmed:languageenglld:pubmed
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pubmed-article:1083513pubmed:volume15lld:pubmed
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pubmed-article:1083513pubmed:pagination149-54lld:pubmed
pubmed-article:1083513pubmed:dateRevised2004-11-17lld:pubmed
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pubmed-article:1083513pubmed:articleTitleB and T lymphocytes in viral hepatitis.lld:pubmed
pubmed-article:1083513pubmed:publicationTypeJournal Articlelld:pubmed