| pubmed-article:10790374 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:10790374 | lifeskim:mentions | umls-concept:C0237401 | lld:lifeskim |
| pubmed-article:10790374 | lifeskim:mentions | umls-concept:C1167117 | lld:lifeskim |
| pubmed-article:10790374 | lifeskim:mentions | umls-concept:C0030943 | lld:lifeskim |
| pubmed-article:10790374 | lifeskim:mentions | umls-concept:C0598312 | lld:lifeskim |
| pubmed-article:10790374 | lifeskim:mentions | umls-concept:C1546857 | lld:lifeskim |
| pubmed-article:10790374 | lifeskim:mentions | umls-concept:C0205224 | lld:lifeskim |
| pubmed-article:10790374 | pubmed:issue | 9 | lld:pubmed |
| pubmed-article:10790374 | pubmed:dateCreated | 2000-6-15 | lld:pubmed |
| pubmed-article:10790374 | pubmed:abstractText | Cdc45p assembles at replication origins before initia tion and is required for origin firing in Saccharomyces cerevisiae. A heat-inducible cdc45 degron mutant was constructed that promotes rapid degradation of Cdc45p at the restrictive temperature. Consistent with a role in initiation, loss of Cdc45p in G(1) prevents all detectable DNA replication without preventing subsequent entry into mitosis. Loss of Cdc45p activity during S-phase blocks S-phase completion but not activation of replication checkpoints. Using density substitution, we show that after allowing replication fork establishment, Cdc45p inactivation prevents the subsequent progression of individual replication forks. This provides the first direct functional evidence that Cdc45p plays an essential role during elongation. Thus, like the large T antigen in SV40 replication, Cdc45p plays a central role in both initiation and elongation phases of chromosomal DNA replication. | lld:pubmed |
| pubmed-article:10790374 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10790374 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10790374 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10790374 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10790374 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10790374 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10790374 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10790374 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10790374 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10790374 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10790374 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10790374 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10790374 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10790374 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10790374 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10790374 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10790374 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10790374 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10790374 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10790374 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10790374 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10790374 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10790374 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10790374 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10790374 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10790374 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10790374 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10790374 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10790374 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10790374 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10790374 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10790374 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10790374 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10790374 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10790374 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10790374 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10790374 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10790374 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10790374 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10790374 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10790374 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10790374 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10790374 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10790374 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10790374 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10790374 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10790374 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10790374 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10790374 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10790374 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10790374 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10790374 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10790374 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10790374 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10790374 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10790374 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10790374 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10790374 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10790374 | pubmed:language | eng | lld:pubmed |
| pubmed-article:10790374 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10790374 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:10790374 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10790374 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10790374 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10790374 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10790374 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10790374 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10790374 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10790374 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10790374 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:10790374 | pubmed:month | May | lld:pubmed |
| pubmed-article:10790374 | pubmed:issn | 0261-4189 | lld:pubmed |
| pubmed-article:10790374 | pubmed:author | pubmed-author:LabieDD | lld:pubmed |
| pubmed-article:10790374 | pubmed:author | pubmed-author:TerceroJ AJA | lld:pubmed |
| pubmed-article:10790374 | pubmed:author | pubmed-author:DiffleyJ FJF | lld:pubmed |
| pubmed-article:10790374 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:10790374 | pubmed:day | 2 | lld:pubmed |
| pubmed-article:10790374 | pubmed:volume | 19 | lld:pubmed |
| pubmed-article:10790374 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:10790374 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:10790374 | pubmed:pagination | 2082-93 | lld:pubmed |
| pubmed-article:10790374 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
| pubmed-article:10790374 | pubmed:meshHeading | pubmed-meshheading:10790374... | lld:pubmed |
| pubmed-article:10790374 | pubmed:meshHeading | pubmed-meshheading:10790374... | lld:pubmed |
| pubmed-article:10790374 | pubmed:meshHeading | pubmed-meshheading:10790374... | lld:pubmed |
| pubmed-article:10790374 | pubmed:meshHeading | pubmed-meshheading:10790374... | lld:pubmed |
| pubmed-article:10790374 | pubmed:meshHeading | pubmed-meshheading:10790374... | lld:pubmed |
| pubmed-article:10790374 | pubmed:meshHeading | pubmed-meshheading:10790374... | lld:pubmed |
| pubmed-article:10790374 | pubmed:meshHeading | pubmed-meshheading:10790374... | lld:pubmed |
| pubmed-article:10790374 | pubmed:meshHeading | pubmed-meshheading:10790374... | lld:pubmed |
