| pubmed-article:10743912 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:10743912 | lifeskim:mentions | umls-concept:C0009170 | lld:lifeskim |
| pubmed-article:10743912 | lifeskim:mentions | umls-concept:C1280500 | lld:lifeskim |
| pubmed-article:10743912 | lifeskim:mentions | umls-concept:C0082060 | lld:lifeskim |
| pubmed-article:10743912 | lifeskim:mentions | umls-concept:C0348016 | lld:lifeskim |
| pubmed-article:10743912 | lifeskim:mentions | umls-concept:C1707455 | lld:lifeskim |
| pubmed-article:10743912 | pubmed:issue | 1 | lld:pubmed |
| pubmed-article:10743912 | pubmed:dateCreated | 2000-6-2 | lld:pubmed |
| pubmed-article:10743912 | pubmed:abstractText | People report that ethanol improves the experience produced by cocaine. This effect may be attributable to cocaethylene (CE), a cocaine metabolite formed only in the presence of ethanol. To test this, rats were trained to run an alley for a single intravenous dose of either cocaine (0.5-2.0 mg/kg) or an equimolar dose of CE (0.75-2.88 mg/kg). The rats' start latency and running speed measured the reinforcing effects of the drugs and the number of times rats approached but failed to enter the goal box (i.e., approach-avoidance retreats) indexed anxiety. Rats reinforced with CE had shorter start latencies and faster running speeds and exhibited fewer "retreats" than cocaine-reinforced rats. These results suggest that CE is more reinforcing and less anxiogenic than cocaine and hence may account for the combined effects of cocaine and ethanol in humans. | lld:pubmed |
| pubmed-article:10743912 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10743912 | pubmed:language | eng | lld:pubmed |
| pubmed-article:10743912 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10743912 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:10743912 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10743912 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10743912 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10743912 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:10743912 | pubmed:month | Feb | lld:pubmed |
| pubmed-article:10743912 | pubmed:issn | 1064-1297 | lld:pubmed |
| pubmed-article:10743912 | pubmed:author | pubmed-author:EttenbergAA | lld:pubmed |
| pubmed-article:10743912 | pubmed:author | pubmed-author:NecessaryB... | lld:pubmed |
| pubmed-article:10743912 | pubmed:author | pubmed-author:RavenM AMA | lld:pubmed |
| pubmed-article:10743912 | pubmed:author | pubmed-author:DanluckD ADA | lld:pubmed |
| pubmed-article:10743912 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:10743912 | pubmed:volume | 8 | lld:pubmed |
| pubmed-article:10743912 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:10743912 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:10743912 | pubmed:pagination | 117-24 | lld:pubmed |
| pubmed-article:10743912 | pubmed:dateRevised | 2007-11-14 | lld:pubmed |
| pubmed-article:10743912 | pubmed:meshHeading | pubmed-meshheading:10743912... | lld:pubmed |
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| pubmed-article:10743912 | pubmed:meshHeading | pubmed-meshheading:10743912... | lld:pubmed |
| pubmed-article:10743912 | pubmed:meshHeading | pubmed-meshheading:10743912... | lld:pubmed |
| pubmed-article:10743912 | pubmed:meshHeading | pubmed-meshheading:10743912... | lld:pubmed |
| pubmed-article:10743912 | pubmed:meshHeading | pubmed-meshheading:10743912... | lld:pubmed |
| pubmed-article:10743912 | pubmed:year | 2000 | lld:pubmed |
| pubmed-article:10743912 | pubmed:articleTitle | Comparison of the reinforcing and anxiogenic effects of intravenous cocaine and cocaethylene. | lld:pubmed |
| pubmed-article:10743912 | pubmed:affiliation | Department of Psychology, University of California, Santa Barbara, 93109, USA. | lld:pubmed |
| pubmed-article:10743912 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:10743912 | pubmed:publicationType | Comparative Study | lld:pubmed |
| pubmed-article:10743912 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:10743912 | pubmed:publicationType | Research Support, U.S. Gov't, Non-P.H.S. | lld:pubmed |
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