| pubmed-article:10729168 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:10729168 | lifeskim:mentions | umls-concept:C0042760 | lld:lifeskim |
| pubmed-article:10729168 | lifeskim:mentions | umls-concept:C0206679 | lld:lifeskim |
| pubmed-article:10729168 | lifeskim:mentions | umls-concept:C0080194 | lld:lifeskim |
| pubmed-article:10729168 | lifeskim:mentions | umls-concept:C0597357 | lld:lifeskim |
| pubmed-article:10729168 | lifeskim:mentions | umls-concept:C1418960 | lld:lifeskim |
| pubmed-article:10729168 | lifeskim:mentions | umls-concept:C1419142 | lld:lifeskim |
| pubmed-article:10729168 | lifeskim:mentions | umls-concept:C1419143 | lld:lifeskim |
| pubmed-article:10729168 | lifeskim:mentions | umls-concept:C1424869 | lld:lifeskim |
| pubmed-article:10729168 | lifeskim:mentions | umls-concept:C0086597 | lld:lifeskim |
| pubmed-article:10729168 | lifeskim:mentions | umls-concept:C0332261 | lld:lifeskim |
| pubmed-article:10729168 | lifeskim:mentions | umls-concept:C1550548 | lld:lifeskim |
| pubmed-article:10729168 | lifeskim:mentions | umls-concept:C1555714 | lld:lifeskim |
| pubmed-article:10729168 | lifeskim:mentions | umls-concept:C1705654 | lld:lifeskim |
| pubmed-article:10729168 | lifeskim:mentions | umls-concept:C0127400 | lld:lifeskim |
| pubmed-article:10729168 | pubmed:issue | 8 | lld:pubmed |
| pubmed-article:10729168 | pubmed:dateCreated | 2000-4-26 | lld:pubmed |
| pubmed-article:10729168 | pubmed:abstractText | The immunoglobulin-like receptors that mediate entry of herpes simplex virus type 1 (HSV-1) into human cells were found to mediate the direct cell-to-cell spread of wild-type virus. The receptors here designated Nectin1alpha and -delta and Nectin2alpha were originally designated HIgR, PRR1/HveC, and PRR2alpha/HveB, respectively. We report the following. (i) Wild-type HSV-1 spreads from cell to cell in J cells expressing nectin1alpha or nectin1delta but not in parental J cells that are devoid of entry receptors. A monoclonal antibody to nectin1, which blocks entry, also blocked cell-to-cell spread in nectin1-expressing J cells. Moreover, wild-type virus did not spread from a receptor-positive to a receptor-negative cell. (ii) The antibody to nectin1 blocked transmission of wild-type virus in a number of human cell lines, with varying efficiencies, suggesting that nectin1 is the principal mediator of wild-type virus spread in a variety of human cell lines. (iii) Nectin1 did not mediate cell fusion induced by the syncytial strains HSV-1(MP) and HFEM-syn. (iv) Nectin2alpha could serve as a receptor for spread of a mutant virus carrying the L25P substitution in glycoprotein D, but not of wild-type virus, in agreement with its ability to mediate entry of the mutant but not of wild-type virus. | lld:pubmed |
| pubmed-article:10729168 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10729168 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10729168 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10729168 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10729168 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10729168 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10729168 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10729168 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10729168 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10729168 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10729168 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10729168 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10729168 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10729168 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10729168 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10729168 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10729168 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10729168 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10729168 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10729168 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10729168 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10729168 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10729168 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10729168 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10729168 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10729168 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10729168 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10729168 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10729168 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10729168 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10729168 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10729168 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10729168 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10729168 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10729168 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10729168 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10729168 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10729168 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10729168 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10729168 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10729168 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10729168 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10729168 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10729168 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10729168 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10729168 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10729168 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10729168 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10729168 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10729168 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10729168 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10729168 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10729168 | pubmed:language | eng | lld:pubmed |
| pubmed-article:10729168 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10729168 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:10729168 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10729168 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10729168 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10729168 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10729168 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10729168 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10729168 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:10729168 | pubmed:month | Apr | lld:pubmed |
| pubmed-article:10729168 | pubmed:issn | 0022-538X | lld:pubmed |
| pubmed-article:10729168 | pubmed:author | pubmed-author:LopezMM | lld:pubmed |
| pubmed-article:10729168 | pubmed:author | pubmed-author:Campadelli-Fi... | lld:pubmed |
| pubmed-article:10729168 | pubmed:author | pubmed-author:DubreuilPP | lld:pubmed |
| pubmed-article:10729168 | pubmed:author | pubmed-author:CocchiFF | lld:pubmed |
| pubmed-article:10729168 | pubmed:author | pubmed-author:MenottiLL | lld:pubmed |
| pubmed-article:10729168 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:10729168 | pubmed:volume | 74 | lld:pubmed |
| pubmed-article:10729168 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:10729168 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:10729168 | pubmed:pagination | 3909-17 | lld:pubmed |
| pubmed-article:10729168 | pubmed:dateRevised | 2011-11-17 | lld:pubmed |
| pubmed-article:10729168 | pubmed:meshHeading | pubmed-meshheading:10729168... | lld:pubmed |
| pubmed-article:10729168 | pubmed:meshHeading | pubmed-meshheading:10729168... | lld:pubmed |
| pubmed-article:10729168 | pubmed:meshHeading | pubmed-meshheading:10729168... | lld:pubmed |
| pubmed-article:10729168 | pubmed:meshHeading | pubmed-meshheading:10729168... | lld:pubmed |
| pubmed-article:10729168 | pubmed:meshHeading | pubmed-meshheading:10729168... | lld:pubmed |
| pubmed-article:10729168 | pubmed:meshHeading | pubmed-meshheading:10729168... | lld:pubmed |
| pubmed-article:10729168 | pubmed:meshHeading | pubmed-meshheading:10729168... | lld:pubmed |
