| pubmed-article:10644831 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:10644831 | lifeskim:mentions | umls-concept:C0002017 | lld:lifeskim |
| pubmed-article:10644831 | lifeskim:mentions | umls-concept:C0026179 | lld:lifeskim |
| pubmed-article:10644831 | lifeskim:mentions | umls-concept:C0024204 | lld:lifeskim |
| pubmed-article:10644831 | lifeskim:mentions | umls-concept:C0598312 | lld:lifeskim |
| pubmed-article:10644831 | pubmed:issue | Pt 2 | lld:pubmed |
| pubmed-article:10644831 | pubmed:dateCreated | 2000-2-29 | lld:pubmed |
| pubmed-article:10644831 | pubmed:abstractText | Aleutian mink disease parvovirus (ADV), causes an immune disorder with a persistent infection of lymphoid organs in adult mink. We studied replication of ADV in gel-supported histocultures prepared from adult mink mesenteric lymph node (MLN). Evidence of virus replication in the histocultures was first observed by indirect immunofluorescence 72 h after incubation with virus. Cells resembling lymphocytes and macrophages contained both ADV capsid (VP2) and nonstructural (NS1 and NS2) proteins, and were present in a distribution suggestive of infected cells within germinal centres. ADV replicative form and encapsidated virion DNA were also detected in infected histocultures at time-points after 72 h. In addition, we were able to passage ADV-Utah to a new round of histocultures. These results suggested that the infected cells were actual target cells for ADV replication and that productive ADV-Utah replication, complete with the generation of virus, was occurring in the histocultures. The mink MLN histocultures provide a system to study the replication and molecular pathogenesis of ADV in target tissues. | lld:pubmed |
| pubmed-article:10644831 | pubmed:language | eng | lld:pubmed |
| pubmed-article:10644831 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10644831 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:10644831 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10644831 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10644831 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:10644831 | pubmed:month | Feb | lld:pubmed |
| pubmed-article:10644831 | pubmed:issn | 0022-1317 | lld:pubmed |
| pubmed-article:10644831 | pubmed:author | pubmed-author:BloomM EME | lld:pubmed |
| pubmed-article:10644831 | pubmed:author | pubmed-author:AastedBB | lld:pubmed |
| pubmed-article:10644831 | pubmed:author | pubmed-author:JensenK TKT | lld:pubmed |
| pubmed-article:10644831 | pubmed:author | pubmed-author:WolfinbargerJ... | lld:pubmed |
| pubmed-article:10644831 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:10644831 | pubmed:volume | 81 | lld:pubmed |
| pubmed-article:10644831 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:10644831 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:10644831 | pubmed:pagination | 335-43 | lld:pubmed |
| pubmed-article:10644831 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:10644831 | pubmed:meshHeading | pubmed-meshheading:10644831... | lld:pubmed |
| pubmed-article:10644831 | pubmed:meshHeading | pubmed-meshheading:10644831... | lld:pubmed |
| pubmed-article:10644831 | pubmed:meshHeading | pubmed-meshheading:10644831... | lld:pubmed |
| pubmed-article:10644831 | pubmed:meshHeading | pubmed-meshheading:10644831... | lld:pubmed |
| pubmed-article:10644831 | pubmed:meshHeading | pubmed-meshheading:10644831... | lld:pubmed |
| pubmed-article:10644831 | pubmed:meshHeading | pubmed-meshheading:10644831... | lld:pubmed |
| pubmed-article:10644831 | pubmed:meshHeading | pubmed-meshheading:10644831... | lld:pubmed |
| pubmed-article:10644831 | pubmed:meshHeading | pubmed-meshheading:10644831... | lld:pubmed |
| pubmed-article:10644831 | pubmed:meshHeading | pubmed-meshheading:10644831... | lld:pubmed |
| pubmed-article:10644831 | pubmed:meshHeading | pubmed-meshheading:10644831... | lld:pubmed |
| pubmed-article:10644831 | pubmed:meshHeading | pubmed-meshheading:10644831... | lld:pubmed |
| pubmed-article:10644831 | pubmed:year | 2000 | lld:pubmed |
| pubmed-article:10644831 | pubmed:articleTitle | Replication of Aleutian mink disease parvovirus in mink lymph node histocultures. | lld:pubmed |
| pubmed-article:10644831 | pubmed:affiliation | Laboratory of Persistent Viral Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rocky Mountain Laboratories, Hamilton, MT 59840, USA. | lld:pubmed |
| pubmed-article:10644831 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:10644831 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10644831 | lld:pubmed |
