| pubmed-article:10612589 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:10612589 | lifeskim:mentions | umls-concept:C0040676 | lld:lifeskim |
| pubmed-article:10612589 | lifeskim:mentions | umls-concept:C0243077 | lld:lifeskim |
| pubmed-article:10612589 | pubmed:issue | 23 | lld:pubmed |
| pubmed-article:10612589 | pubmed:dateCreated | 2000-1-13 | lld:pubmed |
| pubmed-article:10612589 | pubmed:abstractText | The design and syntheses of non-thiol inhibitors of farnesyl-protein transferase are described. Optimization of cysteine-substituted diarylethers led to highly potent imidazole-containing diarylethers and diarylsulfones. Polar diaryl linkers dramatically improved potency and gave highly cell active compounds. | lld:pubmed |
| pubmed-article:10612589 | pubmed:language | eng | lld:pubmed |
| pubmed-article:10612589 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10612589 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:10612589 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10612589 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10612589 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10612589 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10612589 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10612589 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10612589 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:10612589 | pubmed:month | Dec | lld:pubmed |
| pubmed-article:10612589 | pubmed:issn | 0960-894X | lld:pubmed |
| pubmed-article:10612589 | pubmed:author | pubmed-author:LieTT | lld:pubmed |
| pubmed-article:10612589 | pubmed:author | pubmed-author:RandsEE | lld:pubmed |
| pubmed-article:10612589 | pubmed:author | pubmed-author:O'NeillT JTJ | lld:pubmed |
| pubmed-article:10612589 | pubmed:author | pubmed-author:OliffA IAI | lld:pubmed |
| pubmed-article:10612589 | pubmed:author | pubmed-author:WilliamsT MTM | lld:pubmed |
| pubmed-article:10612589 | pubmed:author | pubmed-author:GrahamS LSL | lld:pubmed |
| pubmed-article:10612589 | pubmed:author | pubmed-author:GibbsJ BJB | lld:pubmed |
| pubmed-article:10612589 | pubmed:author | pubmed-author:KohlN ENE | lld:pubmed |
| pubmed-article:10612589 | pubmed:author | pubmed-author:HartmanG DGD | lld:pubmed |
| pubmed-article:10612589 | pubmed:author | pubmed-author:KoblanK SKS | lld:pubmed |
| pubmed-article:10612589 | pubmed:author | pubmed-author:CulbersonJ... | lld:pubmed |
| pubmed-article:10612589 | pubmed:author | pubmed-author:LobellR BRB | lld:pubmed |
| pubmed-article:10612589 | pubmed:author | pubmed-author:DinsmoreC JCJ | lld:pubmed |
| pubmed-article:10612589 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:10612589 | pubmed:day | 6 | lld:pubmed |
| pubmed-article:10612589 | pubmed:volume | 9 | lld:pubmed |
| pubmed-article:10612589 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:10612589 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:10612589 | pubmed:pagination | 3301-6 | lld:pubmed |
| pubmed-article:10612589 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:10612589 | pubmed:meshHeading | pubmed-meshheading:10612589... | lld:pubmed |
| pubmed-article:10612589 | pubmed:meshHeading | pubmed-meshheading:10612589... | lld:pubmed |
| pubmed-article:10612589 | pubmed:meshHeading | pubmed-meshheading:10612589... | lld:pubmed |
| pubmed-article:10612589 | pubmed:meshHeading | pubmed-meshheading:10612589... | lld:pubmed |
| pubmed-article:10612589 | pubmed:meshHeading | pubmed-meshheading:10612589... | lld:pubmed |
| pubmed-article:10612589 | pubmed:meshHeading | pubmed-meshheading:10612589... | lld:pubmed |
| pubmed-article:10612589 | pubmed:meshHeading | pubmed-meshheading:10612589... | lld:pubmed |
| pubmed-article:10612589 | pubmed:meshHeading | pubmed-meshheading:10612589... | lld:pubmed |
| pubmed-article:10612589 | pubmed:year | 1999 | lld:pubmed |
| pubmed-article:10612589 | pubmed:articleTitle | Imidazole-containing diarylether and diarylsulfone inhibitors of farnesyl-protein transferase. | lld:pubmed |
| pubmed-article:10612589 | pubmed:affiliation | Department of Medicinal Chemistry, Merck Research Laboratories, West Point, PA 19486, USA. | lld:pubmed |
| pubmed-article:10612589 | pubmed:publicationType | Journal Article | lld:pubmed |
| http://linkedlifedata.com/r... | http://linkedlifedata.com/r... | pubmed-article:10612589 | lld:chembl |
