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pubmed-article:10567877pubmed:abstractTextThe use of prostate-specific antigen (PSA) in the diagnosis of prostate cancer is controversial due to false-positive results caused by benign prostatic hyperplasia. Several groups have suggested the usefulness of the percentage of free PSA (%fPSA) in patients with PSA levels between 4 and 10 microg/l. Based on previously obtained results, biopsy is carried out in our hospital if the PSA is greater than 10 microg/l or if the %fPSA is lower than 20% and PSA is between 4-10 microg/l. In this study, we have compared these results with those obtained with a logistic regression model based on the determination of PSA and %fPSA. The diagnostic efficacy of the logistic regression model is greater than that of the currently used model. The posterior construction of a nomogram based on the data obtained greatly facilitates the application of the logistic regression model.lld:pubmed
pubmed-article:10567877pubmed:languageenglld:pubmed
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pubmed-article:10567877pubmed:statusMEDLINElld:pubmed
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pubmed-article:10567877pubmed:authorpubmed-author:CarreteroPPlld:pubmed
pubmed-article:10567877pubmed:authorpubmed-author:MolinaRRlld:pubmed
pubmed-article:10567877pubmed:authorpubmed-author:FilellaXXlld:pubmed
pubmed-article:10567877pubmed:authorpubmed-author:BallestaA MAMlld:pubmed
pubmed-article:10567877pubmed:authorpubmed-author:AlcoverJJlld:pubmed
pubmed-article:10567877pubmed:authorpubmed-author:QuintóLLlld:pubmed
pubmed-article:10567877pubmed:authorpubmed-author:Bosch-Capblan...lld:pubmed
pubmed-article:10567877pubmed:copyrightInfoCopyright 1999 S. Karger AG, Basellld:pubmed
pubmed-article:10567877pubmed:issnTypePrintlld:pubmed
pubmed-article:10567877pubmed:volume20lld:pubmed
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pubmed-article:10567877pubmed:pagination312-8lld:pubmed
pubmed-article:10567877pubmed:dateRevised2010-1-15lld:pubmed
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pubmed-article:10567877pubmed:articleTitleEvaluation of a multivariate prostate-specific antigen and percentage of free prostate-specific antigen logistic regression model in the diagnosis of prostate cancer.lld:pubmed
pubmed-article:10567877pubmed:affiliationDepartment of Clinical Biochemistry (Unit for Cancer Research), 'Institut d'Investigacions Biomèdiques August Pi i Sunyer', Hospital Clínic, Barcelona, Spain. xfilella@medicina.ub.eslld:pubmed
pubmed-article:10567877pubmed:publicationTypeJournal Articlelld:pubmed