pubmed-article:10513588 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:10513588 | lifeskim:mentions | umls-concept:C0027882 | lld:lifeskim |
pubmed-article:10513588 | lifeskim:mentions | umls-concept:C0087140 | lld:lifeskim |
pubmed-article:10513588 | lifeskim:mentions | umls-concept:C0014406 | lld:lifeskim |
pubmed-article:10513588 | lifeskim:mentions | umls-concept:C0017262 | lld:lifeskim |
pubmed-article:10513588 | lifeskim:mentions | umls-concept:C1709059 | lld:lifeskim |
pubmed-article:10513588 | lifeskim:mentions | umls-concept:C2911684 | lld:lifeskim |
pubmed-article:10513588 | lifeskim:mentions | umls-concept:C0185117 | lld:lifeskim |
pubmed-article:10513588 | pubmed:issue | 2 | lld:pubmed |
pubmed-article:10513588 | pubmed:dateCreated | 1999-11-22 | lld:pubmed |
pubmed-article:10513588 | pubmed:abstractText | We have reported previously that exposure to environmental novelty enhances the behavioral activating effects of amphetamine and its ability to induce the immediate early gene c-fos in the striatum and in other brain regions. In the present study, we used double in situ hybridization histochemistry to study the effect of amphetamine and/or novelty on c-fos expression in two populations of striatal neurons that preferentially express either D1 or D2 dopamine receptor mRNA. When given intraperitoneally to rats in their home cage, amphetamine (2.0 mg/kg) increased c-fos expression only in D1 neurons. In contrast, when the same dose of amphetamine was administered to rats in a novel environment, c-fos was increased in both D1 and D2 neurons. We conclude that the neural populations engaged by amphetamine vary as a function of the circumstances surrounding its administration. | lld:pubmed |
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pubmed-article:10513588 | pubmed:language | eng | lld:pubmed |
pubmed-article:10513588 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:10513588 | pubmed:citationSubset | IM | lld:pubmed |
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pubmed-article:10513588 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:10513588 | pubmed:month | Sep | lld:pubmed |
pubmed-article:10513588 | pubmed:issn | 0166-4328 | lld:pubmed |
pubmed-article:10513588 | pubmed:author | pubmed-author:RobinsonT ETE | lld:pubmed |
pubmed-article:10513588 | pubmed:author | pubmed-author:WatsonS JSJ | lld:pubmed |
pubmed-article:10513588 | pubmed:author | pubmed-author:AkilHH | lld:pubmed |
pubmed-article:10513588 | pubmed:author | pubmed-author:KIMS KSK | lld:pubmed |
pubmed-article:10513588 | pubmed:author | pubmed-author:BadianeMM | lld:pubmed |
pubmed-article:10513588 | pubmed:author | pubmed-author:OatesM MMM | lld:pubmed |
pubmed-article:10513588 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:10513588 | pubmed:volume | 103 | lld:pubmed |
pubmed-article:10513588 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:10513588 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:10513588 | pubmed:pagination | 203-9 | lld:pubmed |
pubmed-article:10513588 | pubmed:dateRevised | 2007-11-14 | lld:pubmed |
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pubmed-article:10513588 | pubmed:meshHeading | pubmed-meshheading:10513588... | lld:pubmed |
pubmed-article:10513588 | pubmed:year | 1999 | lld:pubmed |
pubmed-article:10513588 | pubmed:articleTitle | Environmental modulation of amphetamine-induced c-fos expression in D1 versus D2 striatal neurons. | lld:pubmed |
pubmed-article:10513588 | pubmed:affiliation | Biopsychology, Department of Psychology, The University of Michigan, Ann Arbor 48109-1109, USA. alducci@umich.edu | lld:pubmed |
pubmed-article:10513588 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:10513588 | pubmed:publicationType | Comparative Study | lld:pubmed |
pubmed-article:10513588 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
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