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pubmed-article:10499955pubmed:abstractTextWe describe the case of an adolescent girl who received high-dose metoclopramide in combination with oral N-acetylcysteine therapy for acute acetaminophen toxicity. Whole blood-sample analysis for abnormal hemoglobin pigments established the diagnosis of sulfhemoglobinemia. Metoclopramide has been shown to cause sulfhemoglobinemia, particularly when used in repeated high doses. Although N-acetylcysteine alone has not been associated as the cause, we suggest that sulfhemoglobine-mia is a potential complication in patients treated with metoclopramide for the nausea that often accompanies oral N-acetylcysteine therapy for acetaminophen toxicity. Cyanosis without respiratory distress should suggest this diagnosis.lld:pubmed
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pubmed-article:10499955pubmed:authorpubmed-author:SheikhSSlld:pubmed
pubmed-article:10499955pubmed:authorpubmed-author:LangfordJ SJSlld:pubmed
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pubmed-article:10499955pubmed:dateRevised2004-11-17lld:pubmed
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pubmed-article:10499955pubmed:year1999lld:pubmed
pubmed-article:10499955pubmed:articleTitleAn adolescent case of sulfhemoglobinemia associated with high-dose metoclopramide and N-acetylcysteine.lld:pubmed
pubmed-article:10499955pubmed:affiliationDepartment of Emergency Medicine, Pediatric Pulmonary Division, University of Louisville, Louisville, KY. jslhnl@bluegrass.netlld:pubmed
pubmed-article:10499955pubmed:publicationTypeJournal Articlelld:pubmed
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