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pubmed-article:10497891pubmed:abstractTextIn this work we investigate the possible toxicity of vanadyl sulfate (VOSO4), a compound capable of reducing hyperglycemia, on the following serum enzymes of diabetic young rats: alanine aminotransferase (ALT), aspartate aminotransferase (AST), lactate dehydrogenase (LD) and creatine kinase (CK), as well as its effects on serum lipids. We find that at a concentration of 1 mg/mL VOSO4 has no toxic effect on the liver and muscles of diabetics young rats. These findings suggest that VOSO4 may be an alternative to insulin in the near future, due to its low cost, low toxicity and ready availability.lld:pubmed
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pubmed-article:10497891pubmed:pagination157-61lld:pubmed
pubmed-article:10497891pubmed:dateRevised2006-11-15lld:pubmed
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pubmed-article:10497891pubmed:articleTitleEffect of oral vanadyl sulfate treatment on serum enzymes and lipids of streptozotocin-diabetic young rats.lld:pubmed
pubmed-article:10497891pubmed:affiliationDepartment of Clinical Analysis, Faculty of Pharmaceutical Sciences of Araraquara, UNESP, SP, Brazil.lld:pubmed
pubmed-article:10497891pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:10497891pubmed:publicationTypeResearch Support, Non-U.S. Gov'tlld:pubmed