| pubmed-article:10484502 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:10484502 | lifeskim:mentions | umls-concept:C0007450 | lld:lifeskim |
| pubmed-article:10484502 | lifeskim:mentions | umls-concept:C0018810 | lld:lifeskim |
| pubmed-article:10484502 | lifeskim:mentions | umls-concept:C0037322 | lld:lifeskim |
| pubmed-article:10484502 | lifeskim:mentions | umls-concept:C0441655 | lld:lifeskim |
| pubmed-article:10484502 | lifeskim:mentions | umls-concept:C0332281 | lld:lifeskim |
| pubmed-article:10484502 | lifeskim:mentions | umls-concept:C0039829 | lld:lifeskim |
| pubmed-article:10484502 | pubmed:issue | 3 Pt 2 | lld:pubmed |
| pubmed-article:10484502 | pubmed:dateCreated | 1999-10-18 | lld:pubmed |
| pubmed-article:10484502 | pubmed:abstractText | Rapid eye movement (REM) sleep is characterized by periods of profound cardiac autonomic activation evident in heart rate surges in humans and canines. Our goals were to determine whether or not the heart rate surge phenomenon occurs in cats and to characterize concurrent central nervous system activity. Cortical and hippocampal electroencephalogram, electromyogram, electrooculogram, pontogeniculooccipital (PGO) waves, subcutaneous electrocardiogram, and respiration were recorded. Bouts of sinus tachycardia lasting >/=3.5 s achieved a rate of 210 beats/min and were present predominantly during REM sleep. Heart rate during the surges rose an average of 26.4% from 132.5 +/- 2.0 beats/min before the surge to 167.5 +/- 2.6 beats/min (P < 0.001) and returned to 130.7 +/- 2.6 beats/min (P < 0.001). The heart rate surges were invariably accompanied by increased incidence and frequency of hippocampal theta waves and increased PGO wave frequency and incidence of PGO wave clusters and eye movement clusters. The occurrence of surges was dramatically reduced from 0.11 +/- 0.03 to 0.01 +/- 0.01/15 s of REM sleep (P = 0.02) by atenolol (0.6 mg/kg iv), indicating that the phenomenon is beta(1)-adrenergically mediated. These findings suggest a coupling between central activation of cardiac sympathetic nerves and the generation of hippocampal theta waves and PGO activity. | lld:pubmed |
| pubmed-article:10484502 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10484502 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10484502 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10484502 | pubmed:language | eng | lld:pubmed |
| pubmed-article:10484502 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10484502 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:10484502 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:10484502 | pubmed:month | Sep | lld:pubmed |
| pubmed-article:10484502 | pubmed:issn | 0002-9513 | lld:pubmed |
| pubmed-article:10484502 | pubmed:author | pubmed-author:VerrierR LRL | lld:pubmed |
| pubmed-article:10484502 | pubmed:author | pubmed-author:HobsonJ AJA | lld:pubmed |
| pubmed-article:10484502 | pubmed:author | pubmed-author:KocsisBB | lld:pubmed |
| pubmed-article:10484502 | pubmed:author | pubmed-author:MorenoRR | lld:pubmed |
| pubmed-article:10484502 | pubmed:author | pubmed-author:LIUP NPN | lld:pubmed |
| pubmed-article:10484502 | pubmed:author | pubmed-author:RoweKK | lld:pubmed |
| pubmed-article:10484502 | pubmed:author | pubmed-author:NearingB DBD | lld:pubmed |
| pubmed-article:10484502 | pubmed:author | pubmed-author:QuattrochiJJ | lld:pubmed |
| pubmed-article:10484502 | pubmed:author | pubmed-author:Wallooppillai... | lld:pubmed |
| pubmed-article:10484502 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:10484502 | pubmed:volume | 277 | lld:pubmed |
| pubmed-article:10484502 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:10484502 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:10484502 | pubmed:pagination | R843-9 | lld:pubmed |
| pubmed-article:10484502 | pubmed:dateRevised | 2007-11-14 | lld:pubmed |
| pubmed-article:10484502 | pubmed:meshHeading | pubmed-meshheading:10484502... | lld:pubmed |
| pubmed-article:10484502 | pubmed:meshHeading | pubmed-meshheading:10484502... | lld:pubmed |
| pubmed-article:10484502 | pubmed:meshHeading | pubmed-meshheading:10484502... | lld:pubmed |
| pubmed-article:10484502 | pubmed:meshHeading | pubmed-meshheading:10484502... | lld:pubmed |
| pubmed-article:10484502 | pubmed:meshHeading | pubmed-meshheading:10484502... | lld:pubmed |
| pubmed-article:10484502 | pubmed:meshHeading | pubmed-meshheading:10484502... | lld:pubmed |
| pubmed-article:10484502 | pubmed:year | 1999 | lld:pubmed |
| pubmed-article:10484502 | pubmed:articleTitle | Heart rate surges during REM sleep are associated with theta rhythm and PGO activity in cats. | lld:pubmed |
| pubmed-article:10484502 | pubmed:affiliation | Institute for Prevention of Cardiovascular Disease, Beth Israel Deaconess Medical Center, Boston, Massachusetts 02215, USA. | lld:pubmed |
| pubmed-article:10484502 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:10484502 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10484502 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10484502 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10484502 | lld:pubmed |
